CHEBI:338412 - (−)-anisomycin

ChEBI IDCHEBI:338412
ChEBI Name(−)-anisomycin
Stars
ASCII Name(-)-anisomycin
DefinitionAn antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
Secondary ChEBI IDsCHEBI:2737, CHEBI:40748
Last Modified23 April 2020
DownloadsMolfile
FormulaC14H19NO4
Net Charge0
Average Mass265.309
Monoisotopic Mass265.13141
SMILES[H][C@]1(Cc2ccc(OC)cc2)NC[C@H](O)[C@H]1OC(C)=O
InChIInChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1
InChIKeyYKJYKKNCCRKFSL-RDBSUJKOSA-N
Wikipedia
Roles Classification
Biological Roles:
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
DNA synthesis inhibitor  Any substance that inhibits the synthesis of DNA.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Applications:
antiparasitic agent  A substance used to treat or prevent parasitic infections.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
(−)-anisomycin (CHEBI:338412) has role anticoronaviral agent (CHEBI:149553)
(−)-anisomycin (CHEBI:338412) has role antimicrobial agent (CHEBI:33281)
(−)-anisomycin (CHEBI:338412) has role antineoplastic agent (CHEBI:35610)
(−)-anisomycin (CHEBI:338412) has role antiparasitic agent (CHEBI:35442)
(−)-anisomycin (CHEBI:338412) has role bacterial metabolite (CHEBI:76969)
(−)-anisomycin (CHEBI:338412) has role DNA synthesis inhibitor (CHEBI:59517)
(−)-anisomycin (CHEBI:338412) has role protein synthesis inhibitor (CHEBI:48001)
(−)-anisomycin (CHEBI:338412) is a monohydroxypyrrolidine (CHEBI:46777)
(−)-anisomycin (CHEBI:338412) is a organonitrogen heterocyclic antibiotic (CHEBI:25558)
IUPAC Name 
(2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate
Synonyms  Source
1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetateChemIDplus
2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetateChemIDplus
2-p-Methoxyphenylmethyl-3-acetoxy-4-hydroxypyrrolidineChemIDplus
AnisomycinKEGG COMPOUND
Manual XrefsDatabases
AnisomycinWikipedia
ANMPDBeChem
C11281KEGG COMPOUND
DB07374DrugBank
LSM-4047LINCS
Registry NumbersSources
Reaxys:20705Reaxys
CAS:22862-76-6ChemIDplus
CAS:22862-76-6KEGG COMPOUND
Citations