CHEBI:338412 - (−)-anisomycin

ChEBI IDCHEBI:338412
ChEBI Name(−)-anisomycin
Stars
ASCII Name(-)-anisomycin
DefinitionAn antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
Secondary ChEBI IDsCHEBI:2737, CHEBI:40748
Last Modified23 April 2020
DownloadsMolfile
FormulaC14H19NO4
Net Charge0
Average Mass265.309
Monoisotopic Mass265.13141
SMILES[H][C@]1(Cc2ccc(OC)cc2)NC[C@H](O)[C@H]1OC(C)=O
InChIInChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1
InChIKeyYKJYKKNCCRKFSL-RDBSUJKOSA-N
Wikipedia
Roles Classification
Biological Roles:
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
DNA synthesis inhibitor  Any substance that inhibits the synthesis of DNA.
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antiparasitic agent  A substance used to treat or prevent parasitic infections.
ChEBI Ontology
Outgoing Relation(s)
(−)-anisomycin (CHEBI:338412) has role anticoronaviral agent (CHEBI:149553)
(−)-anisomycin (CHEBI:338412) has role antimicrobial agent (CHEBI:33281)
(−)-anisomycin (CHEBI:338412) has role antineoplastic agent (CHEBI:35610)
(−)-anisomycin (CHEBI:338412) has role antiparasitic agent (CHEBI:35442)
(−)-anisomycin (CHEBI:338412) has role bacterial metabolite (CHEBI:76969)
(−)-anisomycin (CHEBI:338412) has role DNA synthesis inhibitor (CHEBI:59517)
(−)-anisomycin (CHEBI:338412) has role protein synthesis inhibitor (CHEBI:48001)
(−)-anisomycin (CHEBI:338412) is a monohydroxypyrrolidine (CHEBI:46777)
(−)-anisomycin (CHEBI:338412) is a organonitrogen heterocyclic antibiotic (CHEBI:25558)
IUPAC Name 
(2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate
Synonyms  Source
1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetateChemIDplus
2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetateChemIDplus
2-p-Methoxyphenylmethyl-3-acetoxy-4-hydroxypyrrolidineChemIDplus
AnisomycinKEGG COMPOUND
Manual XrefsDatabases
AnisomycinWikipedia
ANMPDBeChem
C11281KEGG COMPOUND
DB07374DrugBank
LSM-4047LINCS
Registry NumbersSources
Reaxys:20705Reaxys
CAS:22862-76-6ChemIDplus
CAS:22862-76-6KEGG COMPOUND
Citations