EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:3374 - capsaicin
| Formula | C18H27NO3 |
| Net Charge | 0 |
| Average Mass | 305.418 |
| Monoisotopic Mass | 305.19909 |
| SMILES | COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O |
| InChI | InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+ |
| InChIKey | YKPUWZUDDOIDPM-SOFGYWHQSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Roles: | TRPV1 agonist An agonist at the transient receptor potential vanilloid 1 (TRPV1). anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. voltage-gated sodium channel blocker Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| Applications: | antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. antitussive An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anti-inflammatory agent Any compound that has anti-inflammatory effects. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| capsaicin (CHEBI:3374) has role analgesic (CHEBI:35480) |
| capsaicin (CHEBI:3374) has role anti-HIV agent (CHEBI:64946) |
| capsaicin (CHEBI:3374) has role anti-inflammatory agent (CHEBI:67079) |
| capsaicin (CHEBI:3374) has role antiemetic (CHEBI:50919) |
| capsaicin (CHEBI:3374) has role antihypertensive agent (CHEBI:35674) |
| capsaicin (CHEBI:3374) has role antineoplastic agent (CHEBI:35610) |
| capsaicin (CHEBI:3374) has role antitussive (CHEBI:51177) |
| capsaicin (CHEBI:3374) has role cardiovascular drug (CHEBI:35554) |
| capsaicin (CHEBI:3374) has role neuroprotective agent (CHEBI:63726) |
| capsaicin (CHEBI:3374) has role non-narcotic analgesic (CHEBI:35481) |
| capsaicin (CHEBI:3374) has role TRPV1 agonist (CHEBI:140535) |
| capsaicin (CHEBI:3374) has role voltage-gated sodium channel blocker (CHEBI:38634) |
| capsaicin (CHEBI:3374) is a capsaicinoid (CHEBI:46931) |
| IUPAC Name |
|---|
| (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide |
| INN | Source |
|---|---|
| capsaicina | WHO MedNet |
| Synonyms | Source |
|---|---|
| ALGRX 4975 | ChEMBL |
| ALGRX-4975 | ChEMBL |
| Ausanil | ChEMBL |
| Axsain | ChEMBL |
| Capsaicin | KEGG COMPOUND |
| Capzasin-hp | ChEMBL |
| Brand Names | Source |
|---|---|
| Zacin | ChEMBL |
| Zostrix hp | ChEMBL |
| UniProt Name | Source |
|---|---|
| capsaicin | UniProt |
| Citations |
|---|