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CHEBI:33270 - α-tocotrienol
| Formula | C29H44O2 |
| Net Charge | 0 |
| Average Mass | 424.669 |
| Monoisotopic Mass | 424.33413 |
| SMILES | CC(C)=CCC/C(C)=C/CC/C(C)=C/CC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1 |
| InChI | InChI=1S/C29H44O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1 |
| InChIKey | RZFHLOLGZPDCHJ-XZXLULOTSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | |||
| - | DOI (10.1038/nbt.2488) | ||
| blood (UBERON:0000178) | PubMed (12739983) | ||
| Panax ginseng (ncbitaxon:4054) | - | MetaboLights (MTBLS350) | From MetaboLights |
| Roles Classification |
|---|
| Chemical Roles: | antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. |
| Biological Roles: | plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). ferroptosis inhibitor Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. fat-soluble vitamin (role) Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. vulnerary A drug used in treating and healing of wounds. antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antipsoriatic A drug used to treat psoriasis. hypoglycemic agent A drug which lowers the blood glucose level. antidote Any protective agent counteracting or neutralizing the action of poisons. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antirheumatic drug A drug used to treat rheumatoid arthritis. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. hepatoprotective agent Any compound that is able to prevent damage to the liver. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. anti-asthmatic agent Any compound that has anti-asthmatic effects. renoprotective agent Any compound that is able to prevent damage to the kidneys. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antiparkinson drug A drug used in the treatment of Parkinson's disease. anti-inflammatory agent Any compound that has anti-inflammatory effects. antifibrotic agent Any agent which acts to reduce fibrosis. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| α-tocotrienol (CHEBI:33270) has role ferroptosis inhibitor (CHEBI:173084) |
| α-tocotrienol (CHEBI:33270) has role human metabolite (CHEBI:77746) |
| α-tocotrienol (CHEBI:33270) has role neuroprotective agent (CHEBI:63726) |
| α-tocotrienol (CHEBI:33270) has role plant metabolite (CHEBI:76924) |
| α-tocotrienol (CHEBI:33270) is a tocotrienol (CHEBI:33235) |
| α-tocotrienol (CHEBI:33270) is a vitamin E (CHEBI:33234) |
| IUPAC Name |
|---|
| (2R)-2,5,7,8-tetramethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-chromen-6-ol |
| Synonyms | Source |
|---|---|
| (2R)-2,5,7,8-tetramethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-1-benzopyran-6-ol | IUPAC |
| alpha-tocotrienol | LIPID MAPS |
| alpha-tocotrienol | KEGG COMPOUND |
| zeta1-tocopherol | LIPID MAPS |
| α-tocotrienol | ChemIDplus |
| ζ1-tocopherol | ChemIDplus |
| UniProt Name | Source |
|---|---|
| α-tocotrienol | UniProt |
| Manual Xrefs | Databases |
|---|---|
| 4445512 | ChemSpider |
| Alpha-Tocotrienol | Wikipedia |
| C00035044 | KNApSAcK |
| C14153 | KEGG COMPOUND |
| CPD-15836 | MetaCyc |
| EP2362875 | Patent |
| FDB002434 | FooDB |
| HMDB0006327 | HMDB |
| LMPR02020054 | LIPID MAPS |
| US2010105930 | Patent |
| WO2010051277 | Patent |
| Registry Numbers | Sources |
|---|---|
| Beilstein:45723 | Beilstein |
| Reaxys:5484296 | Reaxys |
| CAS:1721-51-3 | ChemIDplus |
| CAS:1721-51-3 | KEGG COMPOUND |
| Citations |
|---|