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CHEBI:32215 - thiamphenicol
| Formula | C12H15Cl2NO5S |
| Net Charge | 0 |
| Average Mass | 356.227 |
| Monoisotopic Mass | 355.00480 |
| SMILES | CS(=O)(=O)c1ccc([C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl)cc1 |
| InChI | InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1 |
| InChIKey | OTVAEFIXJLOWRX-NXEZZACHSA-N |
| Roles Classification |
|---|
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Application: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| thiamphenicol (CHEBI:32215) has role antimicrobial agent (CHEBI:33281) |
| thiamphenicol (CHEBI:32215) has role immunosuppressive agent (CHEBI:35705) |
| thiamphenicol (CHEBI:32215) is a monocarboxylic acid amide (CHEBI:29347) |
| thiamphenicol (CHEBI:32215) is a sulfone (CHEBI:35850) |
| IUPAC Name |
|---|
| 2,2-dichloro-N-{(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl}acetamide |
| Synonyms | Source |
|---|---|
| Armai (TN) | KEGG DRUG |
| D-(+)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide | ChemIDplus |
| (+)-Thiamphenicol | ChemIDplus |
| Thiamphenicol | KEGG COMPOUND |
| Thiocymetin (TN) | KEGG DRUG |