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CHEBI:32215 - thiamphenicol
| Formula | C12H15Cl2NO5S |
| Net Charge | 0 |
| Average Mass | 356.227 |
| Monoisotopic Mass | 355.00480 |
| SMILES | CS(=O)(=O)c1ccc([C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl)cc1 |
| InChI | InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1 |
| InChIKey | OTVAEFIXJLOWRX-NXEZZACHSA-N |
| Roles Classification |
|---|
| Biological Roles: | antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Application: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| thiamphenicol (CHEBI:32215) has role antibacterial agent (CHEBI:33282) |
| thiamphenicol (CHEBI:32215) has role antimicrobial agent (CHEBI:33281) |
| thiamphenicol (CHEBI:32215) has role immunosuppressive agent (CHEBI:35705) |
| thiamphenicol (CHEBI:32215) is a monocarboxylic acid amide (CHEBI:29347) |
| thiamphenicol (CHEBI:32215) is a sulfone (CHEBI:35850) |
| IUPAC Name |
|---|
| 2,2-dichloro-N-{(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl}acetamide |
| INN | Source |
|---|---|
| tianfenicol | WHO MedNet |
| Synonyms | Source |
|---|---|
| Armai | ChEMBL |
| Armai (TN) | KEGG DRUG |
| Dextrosulphenidol | ChEMBL |
| D-(+)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide | ChemIDplus |
| NSC-522822 | ChEMBL |
| (+)-Thiamphenicol | ChemIDplus |
| Citations |
|---|