EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:32173 - suxibuzone

ChEBI IDCHEBI:32173
ChEBI Namesuxibuzone
Stars
DefinitionA pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.
Last Modified9 November 2017
DownloadsMolfile
FormulaC24H26N2O6
Net Charge0
Average Mass438.480
Monoisotopic Mass438.17909
SMILESCCCCC1(COC(=O)CCC(=O)O)C(=O)N(c2ccccc2)N(c2ccccc2)C1=O
InChIInChI=1S/C24H26N2O6/c1-2-3-16-24(17-32-21(29)15-14-20(27)28)22(30)25(18-10-6-4-7-11-18)26(23(24)31)19-12-8-5-9-13-19/h4-13H,2-3,14-17H2,1H3,(H,27,28)
InChIKeyONWXNHPOAGOMTG-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
antirheumatic drug  A drug used to treat rheumatoid arthritis.
peripheral nervous system drug  A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
ChEBI Ontology
Outgoing Relation(s)
suxibuzone (CHEBI:32173) has role antirheumatic drug (CHEBI:35842)
suxibuzone (CHEBI:32173) has role non-narcotic analgesic (CHEBI:35481)
suxibuzone (CHEBI:32173) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
suxibuzone (CHEBI:32173) has role peripheral nervous system drug (CHEBI:49110)
suxibuzone (CHEBI:32173) has role prodrug (CHEBI:50266)
suxibuzone (CHEBI:32173) is a hemisuccinate (CHEBI:138979)
suxibuzone (CHEBI:32173) is a monocarboxylic acid (CHEBI:25384)
suxibuzone (CHEBI:32173) is a pyrazolidines (CHEBI:38312)
IUPAC Name 
4-[(4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy]-4-oxobutanoic acid
INNs  Source
suxibuzoneKEGG DRUG
suxibuzonaChemIDplus
suxibuzonumChemIDplus
suxibuzoneWHO MedNet
Synonyms  Source
4-Hydroxymethylbutazolidine hemisuccinateChemIDplus
4-Butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedione hydrogen succinateChemIDplus
Manual XrefsDatabases
D01289KEGG DRUG
SuxibuzoneWikipedia
HMDB0042019HMDB
LSM-5851LINCS
2547DrugCentral
1815VSDB
Registry NumbersSources
Reaxys:904563Reaxys
CAS:27470-51-5KEGG DRUG
CAS:27470-51-5ChemIDplus
Citations