CHEBI:32124 - secobarbital sodium

ChEBI IDCHEBI:32124
ChEBI Namesecobarbital sodium
Stars
DefinitionThe monosodium salt of secobarbital.
Last Modified13 December 2010
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Applications:
anaesthesia adjuvant  Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time.
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
ChEBI Ontology
Outgoing Relation(s)
secobarbital sodium (CHEBI:32124) has part secobarbital(1−) (CHEBI:60810)
secobarbital sodium (CHEBI:32124) has role anaesthesia adjuvant (CHEBI:60807)
secobarbital sodium (CHEBI:32124) has role GABA modulator (CHEBI:50268)
secobarbital sodium (CHEBI:32124) has role sedative (CHEBI:35717)
secobarbital sodium (CHEBI:32124) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
sodium 2,4,6-trioxo-5-(pentan-2-yl)-5-(prop-2-en-1-yl)tetrahydro-2H-pyrimidin-1-ide
Synonyms  Source
secobarbitone sodiumChemIDplus
sodium 5-allyl-5-(1-methylbutyl)barbiturateChemIDplus
sodium secobarbitalChemIDplus
Manual XrefsDatabases
D01310KEGG DRUG
DB00418DrugBank
Registry NumbersSources
Reaxys:5369275Reaxys
CAS:309-43-3KEGG DRUG
CAS:309-43-3ChemIDplus