CHEBI:32124 - secobarbital sodium

ChEBI IDCHEBI:32124
ChEBI Namesecobarbital sodium
Stars
DefinitionThe monosodium salt of secobarbital.
Last Modified13 December 2010
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Applications:
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
anaesthesia adjuvant  Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time.
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
secobarbital sodium (CHEBI:32124) has part secobarbital(1−) (CHEBI:60810)
secobarbital sodium (CHEBI:32124) has role anaesthesia adjuvant (CHEBI:60807)
secobarbital sodium (CHEBI:32124) has role GABA modulator (CHEBI:50268)
secobarbital sodium (CHEBI:32124) has role sedative (CHEBI:35717)
secobarbital sodium (CHEBI:32124) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
sodium 2,4,6-trioxo-5-(pentan-2-yl)-5-(prop-2-en-1-yl)tetrahydro-2H-pyrimidin-1-ide
Synonyms  Source
secobarbitone sodiumChemIDplus
sodium 5-allyl-5-(1-methylbutyl)barbiturateChemIDplus
sodium secobarbitalChemIDplus
Manual XrefsDatabases
D01310KEGG DRUG
DB00418DrugBank
Registry NumbersSources
Reaxys:5369275Reaxys
CAS:309-43-3KEGG DRUG
CAS:309-43-3ChemIDplus