EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:32124 |
| ChEBI Name | secobarbital sodium |
| Stars | |
| Definition | The monosodium salt of secobarbital. |
| Last Modified | 13 December 2010 |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. anaesthesia adjuvant Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time. sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| secobarbital sodium (CHEBI:32124) has part secobarbital(1−) (CHEBI:60810) |
| secobarbital sodium (CHEBI:32124) has role anaesthesia adjuvant (CHEBI:60807) |
| secobarbital sodium (CHEBI:32124) has role GABA modulator (CHEBI:50268) |
| secobarbital sodium (CHEBI:32124) has role sedative (CHEBI:35717) |
| secobarbital sodium (CHEBI:32124) is a organic sodium salt (CHEBI:38700) |
| IUPAC Name |
|---|
| sodium 2,4,6-trioxo-5-(pentan-2-yl)-5-(prop-2-en-1-yl)tetrahydro-2H-pyrimidin-1-ide |
| Synonyms | Source |
|---|---|
| sodium 5-allyl-5-(1-methylbutyl)barbiturate | ChemIDplus |
| sodium secobarbital | ChemIDplus |
| secobarbitone sodium | ChemIDplus |