EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:32124 |
| ChEBI Name | secobarbital sodium |
| Stars | |
| Definition | The monosodium salt of secobarbital. |
| Last Modified | 13 December 2010 |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | anaesthesia adjuvant Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| secobarbital sodium (CHEBI:32124) has part secobarbital(1−) (CHEBI:60810) |
| secobarbital sodium (CHEBI:32124) has role anaesthesia adjuvant (CHEBI:60807) |
| secobarbital sodium (CHEBI:32124) has role GABA modulator (CHEBI:50268) |
| secobarbital sodium (CHEBI:32124) has role sedative (CHEBI:35717) |
| secobarbital sodium (CHEBI:32124) is a organic sodium salt (CHEBI:38700) |
| IUPAC Name |
|---|
| sodium 2,4,6-trioxo-5-(pentan-2-yl)-5-(prop-2-en-1-yl)tetrahydro-2H-pyrimidin-1-ide |
| Synonyms | Source |
|---|---|
| secobarbitone sodium | ChemIDplus |
| sodium 5-allyl-5-(1-methylbutyl)barbiturate | ChemIDplus |
| sodium secobarbital | ChemIDplus |