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CHEBI:32004 - pipamperone dihydrochloride

Default Structure
ChEBI IDCHEBI:32004
ChEBI Namepipamperone dihydrochloride
Stars
DefinitionA hydrochloride resulting from the reaction of pipamperone with 2 mol eq. of hydrogen chloride. It is used as an antipsychotic.
Secondary ChEBI IDCHEBI:78944
Last Modified24 June 2014
SubmitterGareth Owen
DownloadsMolfile
FormulaC21H30FN3O2.2HCl
Net Charge0
Average Mass448.410
Monoisotopic Mass447.18556
SMILESCl.Cl.NC(=O)C1(N2CCCCC2)CCN(CCCC(=O)c2ccc(F)cc2)CC1
InChIInChI=1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H
InChIKeyBMXXSXQVMCXGJM-UHFFFAOYSA-N
Roles Classification
Biological Roles:
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
first generation antipsychotic  Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
ChEBI Ontology
Outgoing Relation(s)
pipamperone dihydrochloride (CHEBI:32004) has part pipamperone(2+) (CHEBI:78943)
pipamperone dihydrochloride (CHEBI:32004) has role dopaminergic antagonist (CHEBI:48561)
pipamperone dihydrochloride (CHEBI:32004) has role first generation antipsychotic (CHEBI:65190)
pipamperone dihydrochloride (CHEBI:32004) has role serotonergic antagonist (CHEBI:48279)
pipamperone dihydrochloride (CHEBI:32004) is a hydrochloride (CHEBI:36807)
IUPAC Name 
1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidine-4'-carboxamide dihydrochloride
Synonyms  Source
1'-(3-(p-fluorobenzoyl)propyl)-(1,4'-bipiperidine)-4'-carboxamide dihydrochlorideChEBI
4'-carbamoyl-1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidinium dichlorideIUPAC
p-fluoro-γ-(4-piperidino-4-carbamoylpiperidino)butyrophenone dihydrochlorideChEBI
pipamperone hydrochlorideKEGG DRUG
Brand Names  Source
DipiperonChEBI
PiperonilChEBI
PropitanChemIDplus
Manual XrefsDatabases
D01482KEGG DRUG
Registry NumbersSources
Reaxys:9174635Reaxys
CAS:2448-68-2KEGG DRUG
CAS:2448-68-2ChemIDplus
Citations