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CHEBI:31866 - mosapramine dihydrochloride

ChEBI IDCHEBI:31866
ChEBI Namemosapramine dihydrochloride
Stars
DefinitionA racemate comprising equimolar amounts of (R)- and (S)-mosapramine dihydrochloride.
Last Modified14 January 2021
DownloadsMolfile
FormulaC28H35ClN4O.2HCl
Net Charge0
Average Mass551.990
Monoisotopic Mass550.20329
SMILESCl.Cl.O=C1NC2CCCCN2C12CCN(CCCN1c3ccccc3CCc3ccc(Cl)cc31)CC2
InChIInChI=1S/C28H35ClN4O.2ClH/c29-23-12-11-22-10-9-21-6-1-2-7-24(21)32(25(22)20-23)16-5-15-31-18-13-28(14-19-31)27(34)30-26-8-3-4-17-33(26)28;;/h1-2,6-7,11-12,20,26H,3-5,8-10,13-19H2,(H,30,34);2*1H
InChIKeyCVCDAZZJQWLXHM-UHFFFAOYSA-N
Roles Classification
Biological Role:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
second generation antipsychotic  Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
ChEBI Ontology
Outgoing Relation(s)
mosapramine dihydrochloride (CHEBI:31866) has role dopaminergic antagonist (CHEBI:48561)
mosapramine dihydrochloride (CHEBI:31866) has role second generation antipsychotic (CHEBI:65191)
mosapramine dihydrochloride (CHEBI:31866) is a racemate (CHEBI:60911)
IUPAC Name 
rac-1'-[3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one dihydrochloride
Synonyms  Source
mosapramine dihydrochlorideKEGG DRUG
CreminKEGG DRUG
mosapramine hydrochlorideChemIDplus
mosapramine .2HClChEBI
Manual XrefsDatabases
D01548KEGG DRUG
Registry NumbersSources
CAS:98043-60-8ChemIDplus
Citations