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CHEBI:31783 - lornoxicam

ChEBI IDCHEBI:31783
ChEBI Namelornoxicam
Stars
DefinitionA thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations.
Last Modified22 February 2017
DownloadsMolfile
FormulaC13H10ClN3O4S2
Net Charge0
Average Mass371.827
Monoisotopic Mass370.98013
SMILESCN1C(C(=O)Nc2ccccn2)=C(O)c2sc(Cl)cc2S1(=O)=O
InChIInChI=1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChIKeyWLHQHAUOOXYABV-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
antipyretic  A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
lornoxicam (CHEBI:31783) has role antipyretic (CHEBI:35493)
lornoxicam (CHEBI:31783) has role non-narcotic analgesic (CHEBI:35481)
lornoxicam (CHEBI:31783) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
lornoxicam (CHEBI:31783) is a heteroaryl hydroxy compound (CHEBI:74818)
lornoxicam (CHEBI:31783) is a monocarboxylic acid amide (CHEBI:29347)
lornoxicam (CHEBI:31783) is a organochlorine compound (CHEBI:36683)
lornoxicam (CHEBI:31783) is a pyridines (CHEBI:26421)
lornoxicam (CHEBI:31783) is a thienothiazine (CHEBI:46977)
IUPAC Name 
6-chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
INNs  Source
lornoxicamKEGG DRUG
lornoxicamumDrugBank
lornoxicamWHO MedNet
lornoxicamWHO MedNet
Synonyms  Source
CCRIS 8589ChemIDplus
Ro 13-9297ChemIDplus
ChlortenoxicamChemIDplus
Manual XrefsDatabases
DB06725DrugBank
D01866KEGG DRUG
US2008014272Patent
LornoxicamWikipedia
1609DrugCentral
Registry NumbersSources
Reaxys:1039965Reaxys
CAS:70374-39-9KEGG DRUG
CAS:70374-39-9ChemIDplus
Citations