EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:3173 - bretylium tosylate
| Formula | C11H17BrN.C7H7O3S |
| Net Charge | 0 |
| Average Mass | 414.365 |
| Monoisotopic Mass | 413.06603 |
| SMILES | CC[N+](C)(C)Cc1ccccc1Br.Cc1ccc(S(=O)(=O)[O-])cc1 |
| InChI | InChI=1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1 |
| InChIKey | KVWNWTZZBKCOPM-UHFFFAOYSA-M |
| Roles Classification |
|---|
| Biological Role: | adrenergic antagonist An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. |
| Applications: | anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. adrenergic antagonist An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| bretylium tosylate (CHEBI:3173) has part bretylium (CHEBI:3172) |
| bretylium tosylate (CHEBI:3173) has role adrenergic antagonist (CHEBI:37887) |
| bretylium tosylate (CHEBI:3173) has role anti-arrhythmia drug (CHEBI:38070) |
| bretylium tosylate (CHEBI:3173) has role antihypertensive agent (CHEBI:35674) |
| bretylium tosylate (CHEBI:3173) is a organosulfonate salt (CHEBI:64382) |
| bretylium tosylate (CHEBI:3173) is a quaternary ammonium salt (CHEBI:35273) |
| IUPAC Name |
|---|
| N-(2-bromobenzyl)-N,N-dimethylethanaminium 4-methylbenzenesulfonate |
| INNs | Source |
|---|---|
| tosilate de bretylium | ChemIDplus |
| tosilato de bretilio | ChemIDplus |
| Synonyms | Source |
|---|---|
| (o-bromobenzyl)ethyldimethylammonium p-toluenesulfonate | ChemIDplus |
| 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-methylbenzenesulfonate | ChemIDplus |
| bretylii tosilas | ChemIDplus |
| dimethylethyl-o-bromobenzylammonium-p-toluenesulphonate | ChemIDplus |
| N-ethyl-N-o-bromobenzyl-N,N-dimethylammonium tosylate | ChemIDplus |
| (2-bromobenzyl)ethyldimethylammonium tosylate | ChEBI |