EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:31684 - Ibudilast
| Formula | C14H18N2O |
| Net Charge | 0 |
| Average Mass | 230.311 |
| Monoisotopic Mass | 230.14191 |
| SMILES | CC(C)C(=O)c1c(C(C)C)nn2ccccc12 |
| InChI | InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3 |
| InChIKey | ZJVFLBOZORBYFE-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. antiviral agent A substance that destroys or inhibits replication of viruses. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Ibudilast (CHEBI:31684) has role analgesic (CHEBI:35480) |
| Ibudilast (CHEBI:31684) has role anticoronaviral agent (CHEBI:149553) |
| Ibudilast (CHEBI:31684) has role antineoplastic agent (CHEBI:35610) |
| Ibudilast (CHEBI:31684) has role antiviral agent (CHEBI:22587) |
| Ibudilast (CHEBI:31684) has role immunosuppressive agent (CHEBI:35705) |
| Ibudilast (CHEBI:31684) is a organic molecular entity (CHEBI:50860) |
| Ibudilast (CHEBI:31684) is a pyrazolopyridine (CHEBI:46699) |
| Ibudilast (CHEBI:31684) is a pyrazolopyridine (CHEBI:46699) |
| Synonyms | Source |
|---|---|
| AV-411 | ChEMBL |
| AV411 | ChEMBL |
| Ibudilast | KEGG COMPOUND |
| ketas | DrugCentral |
| KP-305 | DrugCentral |
| MN-166 | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 1406 | DrugCentral |
| D01385 | KEGG DRUG |
| HMDB0015614 | HMDB |
| LSM-2357 | LINCS |
| Registry Numbers | Sources |
|---|---|
| CAS:50847-11-5 | KEGG COMPOUND |
| CAS:50847-11-5 | DrugCentral |
| Citations |
|---|