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CHEBI:31547 - eplerenone

Default Structure
ChEBI IDCHEBI:31547
ChEBI Nameeplerenone
Stars
Last Modified28 October 2019
DownloadsMolfile
FormulaC24H30O6
Net Charge0
Average Mass414.498
Monoisotopic Mass414.20424
SMILES[H][C@@]12CC[C@@]3(CCC(=O)O3)[C@@]1(C)C[C@@]1([H])O[C@@]13[C@@]2([H])[C@H](C(=O)OC)CC1=CC(=O)CC[C@@]13C
InChIInChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1
InChIKeyJUKPWJGBANNWMW-VWBFHTRKSA-N
Wikipedia
Roles Classification
Biological Role:
aldosterone antagonist  A compound which inhibits or antagonizes the biosynthesis or actions of aldosterone.
Applications:
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
aldosterone antagonist  A compound which inhibits or antagonizes the biosynthesis or actions of aldosterone.
hypoglycemic agent  A drug which lowers the blood glucose level.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
ChEBI Ontology
Outgoing Relation(s)
eplerenone (CHEBI:31547) has parent hydride pregnane (CHEBI:8386)
eplerenone (CHEBI:31547) has role aldosterone antagonist (CHEBI:50844)
eplerenone (CHEBI:31547) has role anti-arrhythmia drug (CHEBI:38070)
eplerenone (CHEBI:31547) has role antihypertensive agent (CHEBI:35674)
eplerenone (CHEBI:31547) has role antineoplastic agent (CHEBI:35610)
eplerenone (CHEBI:31547) has role cardiovascular drug (CHEBI:35554)
eplerenone (CHEBI:31547) has role hypoglycemic agent (CHEBI:35526)
eplerenone (CHEBI:31547) is a 3-oxo-Δ4 steroid (CHEBI:47909)
eplerenone (CHEBI:31547) is a epoxy steroid (CHEBI:145217)
eplerenone (CHEBI:31547) is a methyl ester (CHEBI:25248)
eplerenone (CHEBI:31547) is a organic heteropentacyclic compound (CHEBI:38164)
eplerenone (CHEBI:31547) is a oxaspiro compound (CHEBI:37948)
eplerenone (CHEBI:31547) is a steroid acid ester (CHEBI:47887)
eplerenone (CHEBI:31547) is a γ-lactone (CHEBI:37581)
IUPAC Name 
7α-methoxycarbonyl-3-oxo-9,11α-epoxy-17α-pregn-4-ene-21,17-carbolactone
INNs  Source
eplerenonaWHO MedNet
eplerenoneKEGG DRUG
Synonyms  Source
EplerenoneKEGG COMPOUND
EpoxymexrenoneChemIDplus
SC-66110ChEMBL
SC-6611OChEMBL
Brand Name  Source
InspraDrugBank
Manual XrefsDatabases
1032DrugCentral
C12512KEGG COMPOUND
D01115KEGG DRUG
DB00700DrugBank
EplerenoneWikipedia
Registry NumbersSources
CAS:107724-20-9KEGG COMPOUND
CAS:107724-20-9ChemIDplus
Citations