EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:31439 - crotamiton

ChEBI IDCHEBI:31439
ChEBI Namecrotamiton
Stars
DefinitionAn enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred.
Last Modified7 March 2018
DownloadsMolfile
FormulaC13H17NO
Net Charge0
Average Mass203.285
Monoisotopic Mass203.13101
SMILESCC=CC(=O)N(CC)c1ccccc1C
InChIInChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3
InChIKeyDNTGGZPQPQTDQF-UHFFFAOYSA-N
Roles Classification
Applications:
antipruritic drug  A drug, usually applied topically, that relieves pruritus (itching).
scabicide  An acaricide that kills mites of the genus Sarcoptes.
ChEBI Ontology
Outgoing Relation(s)
crotamiton (CHEBI:31439) has role antipruritic drug (CHEBI:59683)
crotamiton (CHEBI:31439) has role scabicide (CHEBI:73333)
crotamiton (CHEBI:31439) is a enamide (CHEBI:51751)
crotamiton (CHEBI:31439) is a tertiary carboxamide (CHEBI:140326)
IUPAC Name 
N-ethyl-N-(2-methylphenyl)but-2-enamide
INNs  Source
crotamitonumChemIDplus
crotamitonChemIDplus
Synonyms  Source
crotonyl-N-ethyl-o-toluidineChemIDplus
N-ethyl-o-crotonotoluidideChemIDplus
crotalginDrugBank
crotamitoneDrugBank
Manual XrefsDatabases
D01381KEGG DRUG
GB615137Patent
DB00265DrugBank
LSM-3274LINCS
744DrugCentral
Registry NumbersSources
Beilstein:3275497Beilstein
CAS:483-63-6KEGG DRUG
CAS:483-63-6ChemIDplus
CAS:483-63-6NIST Chemistry WebBook