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CHEBI:31401 - cilostazol
| Formula | C20H27N5O2 |
| Net Charge | 0 |
| Average Mass | 369.469 |
| Monoisotopic Mass | 369.21648 |
| SMILES | O=C1CCc2cc(OCCCCc3nnnn3C3CCCCC3)ccc2N1 |
| InChI | InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26) |
| InChIKey | RRGUKTPIGVIEKM-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor which interferes with the action of 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17). analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. vasodilator agent A drug used to cause dilation of the blood vessels. vulnerary A drug used in treating and healing of wounds. fibrin modulating drug A drug that affects the function of fibrin in blood coagulation. anticoagulant An agent that prevents blood clotting. platelet aggregation inhibitor A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| cilostazol (CHEBI:31401) has role analgesic (CHEBI:35480) |
| cilostazol (CHEBI:31401) has role antiatherosclerotic agent (CHEBI:145947) |
| cilostazol (CHEBI:31401) has role anticoagulant (CHEBI:50249) |
| cilostazol (CHEBI:31401) has role antirheumatic drug (CHEBI:35842) |
| cilostazol (CHEBI:31401) has role bronchodilator agent (CHEBI:35523) |
| cilostazol (CHEBI:31401) has role cardiovascular drug (CHEBI:35554) |
| cilostazol (CHEBI:31401) has role EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor (CHEBI:50568) |
| cilostazol (CHEBI:31401) has role fibrin modulating drug (CHEBI:48676) |
| cilostazol (CHEBI:31401) has role neuroprotective agent (CHEBI:63726) |
| cilostazol (CHEBI:31401) has role platelet aggregation inhibitor (CHEBI:50427) |
| cilostazol (CHEBI:31401) has role vasodilator agent (CHEBI:35620) |
| cilostazol (CHEBI:31401) has role vulnerary (CHEBI:73336) |
| cilostazol (CHEBI:31401) is a lactam (CHEBI:24995) |
| cilostazol (CHEBI:31401) is a tetrazoles (CHEBI:35689) |
| IUPAC Name |
|---|
| 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one |
| INNs | Source |
|---|---|
| cilostazol | ChemIDplus |
| cilostazolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone | ChemIDplus |
| 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone | ChemIDplus |
| 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril | ChemIDplus |
| 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one | ChEMBL |
| NSC-758936 | ChEMBL |
| OPC-21 | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:3632017 | Beilstein |
| CAS:73963-72-1 | KEGG DRUG |
| CAS:73963-72-1 | ChemIDplus |
| Citations |
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