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CHEBI:31282 - bevantolol hydrochloride
| Formula | C20H28NO4.Cl |
| Net Charge | 0 |
| Average Mass | 381.900 |
| Monoisotopic Mass | 381.17069 |
| SMILES | COc1ccc(CC[NH2+]CC(O)COc2cccc(C)c2)cc1OC.[Cl-] |
| InChI | InChI=1S/C20H27NO4.ClH/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19(23-2)20(12-16)24-3;/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3;1H |
| InChIKey | FJTKCFSPYUMXJB-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | calcium channel blocker One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| Applications: | antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| bevantolol hydrochloride (CHEBI:31282) has part bevantolol (CHEBI:238698) |
| bevantolol hydrochloride (CHEBI:31282) has role anti-arrhythmia drug (CHEBI:38070) |
| bevantolol hydrochloride (CHEBI:31282) has role antihypertensive agent (CHEBI:35674) |
| bevantolol hydrochloride (CHEBI:31282) has role calcium channel blocker (CHEBI:38215) |
| bevantolol hydrochloride (CHEBI:31282) has role β-adrenergic antagonist (CHEBI:35530) |
| bevantolol hydrochloride (CHEBI:31282) is a hydrochloride (CHEBI:36807) |
| Incoming Relation(s) |
| (R)-bevantolol hydrochloride (CHEBI:59186) is a bevantolol hydrochloride (CHEBI:31282) |
| (S)-bevantolol hydrochloride (CHEBI:59187) is a bevantolol hydrochloride (CHEBI:31282) |
| IUPAC Name |
|---|
| 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol hydrochloride |
| Synonyms | Source |
|---|---|
| bevantolol hydrochloride | ChemIDplus |
| bevantolol HCl | ChemIDplus |
| (±)-1-((3,4-dimethoxyphenethyl)amino)-3-(m-tolyloxy)-2-propanol hydrochloride | ChemIDplus |
| 1-(3,4-dimethoxyphenethylamino)-3-m-tolyloxy-propan-2-ol hydrochloride | ChEBI |
| N-[2-(3,4-dimethoxyphenyl)ethyl]-2-hydroxy-3-(3-methylphenoxy)propan-1-aminium chloride | IUPAC |
| Manual Xrefs | Databases |
|---|---|
| D01369 | KEGG DRUG |
| Registry Numbers | Sources |
|---|---|
| Beilstein:5195067 | Beilstein |
| CAS:42864-78-8 | KEGG DRUG |
| CAS:42864-78-8 | ChemIDplus |
| Citations |
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