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CHEBI:3127 - bisoprolol
| Formula | C18H31NO4 |
| Net Charge | 0 |
| Average Mass | 325.449 |
| Monoisotopic Mass | 325.22531 |
| SMILES | CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1 |
| InChI | InChI=1S/C18H31NO4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4/h5-8,14-15,17,19-20H,9-13H2,1-4H3 |
| InChIKey | VHYCDWMUTMEGQY-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | sympatholytic agent Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS). beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| Applications: | anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. sympatholytic agent Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS). antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| bisoprolol (CHEBI:3127) has role anti-arrhythmia drug (CHEBI:38070) |
| bisoprolol (CHEBI:3127) has role antihypertensive agent (CHEBI:35674) |
| bisoprolol (CHEBI:3127) has role sympatholytic agent (CHEBI:66991) |
| bisoprolol (CHEBI:3127) has role β-adrenergic antagonist (CHEBI:35530) |
| bisoprolol (CHEBI:3127) is a secondary alcohol (CHEBI:35681) |
| bisoprolol (CHEBI:3127) is a secondary amine (CHEBI:32863) |
| Incoming Relation(s) |
| bisoprolol fumarate (CHEBI:3128) has part bisoprolol (CHEBI:3127) |
| IUPAC Name |
|---|
| 1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol |
| INNs | Source |
|---|---|
| bisoprolol | WHO MedNet |
| bisoprolol | ChemIDplus |
| bisoprololum | WHO MedNet |
| Synonyms | Source |
|---|---|
| (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol | ChemIDplus |
| Bisoprolol | KEGG COMPOUND |
| (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol | ChemIDplus |
| Registry Numbers | Sources |
|---|---|
| CAS:66722-44-9 | ChemIDplus |