EMBL-EBI | Chemical Biology | ChEBI
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| Formula | C11H12N3O.CH3O4S |
| Net Charge | 0 |
| Average Mass | 313.335 |
| Monoisotopic Mass | 313.07324 |
| SMILES | COS(=O)(=O)[O-].COc1cc(N)cn[n+]1-c1ccccc1 |
| InChI | InChI=1S/C11H11N3O.CH4O4S/c1-15-11-7-9(12)8-13-14(11)10-5-3-2-4-6-10;1-5-6(2,3)4/h2-8,12H,1H3;1H3,(H,2,3,4) |
| InChIKey | ZEASXVYVFFXULL-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
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| Biological Roles: | sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. EC 1.4.3.4 (monoamine oxidase) inhibitor An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4). |
| Applications: | sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. antihypotensive agent A cardiovascular drug that tends to raise reduced blood pressure. adrenergic uptake inhibitor Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| amezinium metilsulfate (CHEBI:31201) has part amezinium (CHEBI:145698) |
| amezinium metilsulfate (CHEBI:31201) has role adrenergic uptake inhibitor (CHEBI:35640) |
| amezinium metilsulfate (CHEBI:31201) has role antihypotensive agent (CHEBI:137431) |
| amezinium metilsulfate (CHEBI:31201) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623) |
| amezinium metilsulfate (CHEBI:31201) has role sympathomimetic agent (CHEBI:35524) |
| amezinium metilsulfate (CHEBI:31201) is a azaheterocycle sulfate salt (CHEBI:38017) |
| IUPAC Name |
|---|
| 4-amino-6-methoxy-1-phenylpyridazin-1-ium methyl sulfate |
| INNs | Source |
|---|---|
| amezinium metilsulfate | WHO MedNet |
| métilsulfate d'amézinium | WHO MedNet |
| metilsulfato de amezinio | WHO MedNet |
| amezinii metilsulfas | WHO MedNet |
| Synonyms | Source |
|---|---|
| amezinium methyl sulfate | ChemIDplus |
| 4-amino-6-methoxy-1-phenyl-pyridazinium methyl sulfate | ChEBI |
| 4-amino-6-methoxy-1-phenylpyridazinium methyl sulfate | ChemIDplus |
| LU-1631 | ChEBI |
| LU 1631 | ChEBI |
| amezinium methylsulfate | ChEBI |
| Brand Names | Source |
|---|---|
| Regulton | DrugCentral |
| Supratonin | ChemIDplus |
| Risumic | KEGG DRUG |
| Tenfortan | ChEBI |
| Acomic | ChEBI |
| Solmfurin | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| D01304 | KEGG DRUG |
| 153 | DrugCentral |
| DB13330 | DrugBank |
| Amezinium_metilsulfate | Wikipedia |
| EP0063267 | Patent |
| Registry Numbers | Sources |
|---|---|
| CAS:30578-37-1 | ChemIDplus |
| Citations |
|---|