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CHEBI:29745 - barbiturate
| Formula | C4H3N2O3 |
| Net Charge | -1 |
| Average Mass | 127.079 |
| Monoisotopic Mass | 127.01492 |
| SMILES | O=C1CC(=O)NC(=O)[N-]1 |
| InChI | InChI=1S/C4H4N2O3/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)/p-1 |
| InChIKey | HNYOPLTXPVRDBG-UHFFFAOYSA-M |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| barbiturate (CHEBI:29745) is a barbiturate anion (CHEBI:22691) |
| barbiturate (CHEBI:29745) is conjugate base of barbituric acid (CHEBI:16294) |
| Incoming Relation(s) |
| barbituric acid (CHEBI:16294) is conjugate acid of barbiturate (CHEBI:29745) |
| IUPAC Name |
|---|
| 2,4,6-trioxotetrahydro-2H-pyrimidin-1-ide |
| Synonym | Source |
|---|---|
| barbiturate anion | NIST Chemistry WebBook |
| Manual Xrefs | Databases |
|---|---|
| C00813 | KEGG COMPOUND |
| Registry Numbers | Sources |
|---|---|
| Gmelin:601777 | Gmelin |