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CHEBI:2896 - astemizole
| Formula | C28H31FN4O |
| Net Charge | 0 |
| Average Mass | 458.581 |
| Monoisotopic Mass | 458.24819 |
| SMILES | COc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1 |
| InChI | InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31) |
| InChIKey | GXDALQBWZGODGZ-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. |
| Applications: | H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. anti-allergic agent A drug used to treat allergic reactions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| astemizole (CHEBI:2896) has role anti-allergic agent (CHEBI:50857) |
| astemizole (CHEBI:2896) has role anticoronaviral agent (CHEBI:149553) |
| astemizole (CHEBI:2896) has role H1-receptor antagonist (CHEBI:37955) |
| astemizole (CHEBI:2896) is a benzimidazoles (CHEBI:22715) |
| astemizole (CHEBI:2896) is a piperidines (CHEBI:26151) |
| IUPAC Name |
|---|
| 1-(4-fluorobenzyl)-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine |
| INNs | Source |
|---|---|
| astemizol | ChemIDplus |
| astemizole | KEGG DRUG |
| astemizolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole | ChemIDplus |
| 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole | ChemIDplus |
| Astemison | ChemIDplus |
| GNF-Pf-2461 | ChEMBL |
| NSC-329963 | ChEMBL |
| NSC-759570 | ChEMBL |
| Brand Name | Source |
|---|---|
| Pollon-eze | ChEMBL |
| Citations |
|---|