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CHEBI:28918 - (R)-adrenaline
| Formula | C9H13NO3 |
| Net Charge | 0 |
| Average Mass | 183.207 |
| Monoisotopic Mass | 183.08954 |
| SMILES | CNC[C@H](O)c1ccc(O)c(O)c1 |
| InChI | InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1 |
| InChIKey | UCTWMZQNUQWSLP-VIFPVBQESA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Mus musculus (ncbitaxon:10090) | - | PubMed (19425150) | Source: BioModels - MODEL1507180067 |
| Roles Classification |
|---|
| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. alpha-adrenergic agonist An agent that selectively binds to and activates α-adrenergic receptors. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. adrenergic agonist An agent that selectively binds to and activates adrenergic receptors. mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. vasodilator agent A drug used to cause dilation of the blood vessels. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. vulnerary A drug used in treating and healing of wounds. anti-inflammatory agent Any compound that has anti-inflammatory effects. alpha-adrenergic agonist An agent that selectively binds to and activates α-adrenergic receptors. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. anti-allergic agent A drug used to treat allergic reactions. hypoglycemic agent A drug which lowers the blood glucose level. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. vasoconstrictor agent Drug used to cause constriction of the blood vessels. adrenergic agonist An agent that selectively binds to and activates adrenergic receptors. antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. nasal decongestant A drug used to relieve nasal congestion in the upper respiratory tract. mydriatic agent Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. anti-asthmatic agent Any compound that has anti-asthmatic effects. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (R)-adrenaline (CHEBI:28918) has role adrenergic agonist (CHEBI:37886) |
| (R)-adrenaline (CHEBI:28918) has role analgesic (CHEBI:35480) |
| (R)-adrenaline (CHEBI:28918) has role anti-allergic agent (CHEBI:50857) |
| (R)-adrenaline (CHEBI:28918) has role anti-arrhythmia drug (CHEBI:38070) |
| (R)-adrenaline (CHEBI:28918) has role anti-asthmatic agent (CHEBI:65023) |
| (R)-adrenaline (CHEBI:28918) has role anti-inflammatory agent (CHEBI:67079) |
| (R)-adrenaline (CHEBI:28918) has role antidepressant (CHEBI:35469) |
| (R)-adrenaline (CHEBI:28918) has role antiglaucoma drug (CHEBI:39456) |
| (R)-adrenaline (CHEBI:28918) has role antiinfective agent (CHEBI:35441) |
| (R)-adrenaline (CHEBI:28918) has role antineoplastic agent (CHEBI:35610) |
| (R)-adrenaline (CHEBI:28918) has role antispasmodic drug (CHEBI:53784) |
| (R)-adrenaline (CHEBI:28918) has role bronchodilator agent (CHEBI:35523) |
| (R)-adrenaline (CHEBI:28918) has role cardiovascular drug (CHEBI:35554) |
| (R)-adrenaline (CHEBI:28918) has role hormone (CHEBI:24621) |
| (R)-adrenaline (CHEBI:28918) has role hypoglycemic agent (CHEBI:35526) |
| (R)-adrenaline (CHEBI:28918) has role mouse metabolite (CHEBI:75771) |
| (R)-adrenaline (CHEBI:28918) has role mydriatic agent (CHEBI:50513) |
| (R)-adrenaline (CHEBI:28918) has role nasal decongestant (CHEBI:77715) |
| (R)-adrenaline (CHEBI:28918) has role sympathomimetic agent (CHEBI:35524) |
| (R)-adrenaline (CHEBI:28918) has role vasoconstrictor agent (CHEBI:50514) |
| (R)-adrenaline (CHEBI:28918) has role vasodilator agent (CHEBI:35620) |
| (R)-adrenaline (CHEBI:28918) has role vulnerary (CHEBI:73336) |
| (R)-adrenaline (CHEBI:28918) has role α-adrenergic agonist (CHEBI:35569) |
| (R)-adrenaline (CHEBI:28918) has role β-adrenergic agonist (CHEBI:35522) |
| (R)-adrenaline (CHEBI:28918) is a 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol (CHEBI:194548) |
| (R)-adrenaline (CHEBI:28918) is conjugate base of (R)-adrenaline(1+) (CHEBI:71406) |
| (R)-adrenaline (CHEBI:28918) is enantiomer of (S)-adrenaline (CHEBI:40751) |
| Incoming Relation(s) |
| (R)-adrenaline hydrochloride (CHEBI:6213) has part (R)-adrenaline (CHEBI:28918) |
| adrenaline (CHEBI:33568) has part (R)-adrenaline (CHEBI:28918) |
| (R)-adrenaline(1+) (CHEBI:71406) is conjugate acid of (R)-adrenaline (CHEBI:28918) |
| (S)-adrenaline (CHEBI:40751) is enantiomer of (R)-adrenaline (CHEBI:28918) |
| IUPAC Name |
|---|
| 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol |
| INNs | Source |
|---|---|
| epinefrina | ChemIDplus |
| epinephrine | ChemIDplus |
| épinéphrine | ChEBI |
| epinephrinum | ChemIDplus |
| Synonyms | Source |
|---|---|
| (−)-3,4-dihydroxy-α-((methylamino)methyl)benzyl alcohol | NIST Chemistry WebBook |
| 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol | KEGG COMPOUND |
| 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol | KEGG COMPOUND |
| Adrenalin | NIST Chemistry WebBook |
| (−)-adrenaline | IUPHAR |
| adrenaline | NIST Chemistry WebBook |
| Brand Names | Source |
|---|---|
| Adrenaclick | ChEMBL |
| Adrenalin | KEGG DRUG |
| Adren co | ChEMBL |
| Ana-guard | ChEMBL |
| Anapen | ChEMBL |
| Anaphylactic shock drug kit | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 1028 | DrugCentral |
| C00029643 | KNApSAcK |
| C00788 | KEGG COMPOUND |
| D00095 | KEGG DRUG |
| DB00668 | DrugBank |
| Epinephrine | Wikipedia |
| HMDB0000068 | HMDB |
| L-EPINEPHRINE | MetaCyc |
| Citations |
|---|