EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:27899 - cisplatin

ChEBI IDCHEBI:27899
ChEBI Namecisplatin
Stars
DefinitionA diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).
Secondary ChEBI IDsCHEBI:3722, CHEBI:23314
Last Modified12 September 2024
DownloadsMolfile

FormulaH6Cl2N2Pt
Net Charge0
Average Mass300.046
Monoisotopic Mass298.95559
SMILES[H][N]([H])([H])[Pt]([Cl])([Cl])[N]([H])([H])[H]
InChIInChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChIKeyLXZZYRPGZAFOLE-UHFFFAOYSA-L

Wikipedia
Roles Classification

ChEBI Ontology
IUPAC Names 
cis-diamminedichloroplatinum(II)
(SP-4-2)-diamminedichloroplatinum
cis-diamminedichloridoplatinum(II)
(SP-4-2)-diamminedichloridoplatinum
INNs  Source
cisplatine  frChemIDplus
cisplatinum  laChemIDplus
cisplatinChemIDplus
cisplatino  esChemIDplus
Synonyms  Source
CisplatinKEGG COMPOUND
cis-[PtCl2(NH3)2]MolBase
cis-dichlorodiammineplatinum(II)ChemIDplus
cis-diamminedichloroplatinumChemIDplus
cis-diammineplatinum(II) dichlorideChemIDplus
cis-DDPChemIDplus
Brand Names  Source
PlatinolKEGG DRUG
BriplatinChemIDplus
CismaplatDrugBank
LederplatinDrugBank
RandaDrugBank
PlatinexDrugBank
Manual XrefsDatabases
C06911KEGG COMPOUND
25MolBase
DB00515DrugBank
DE2318020Patent
DE2329485Patent
D00275KEGG DRUG
CPD0-1392MetaCyc
HMDB0014656HMDB
CisplatinWikipedia
Registry NumbersSources
Gmelin:2519Gmelin
Reaxys:11324567Reaxys
CAS:15663-27-1KEGG COMPOUND
CAS:15663-27-1ChemIDplus
Citations