griseofulvin (CHEBI:27779)

CHEBI:27779 - griseofulvin

ChEBI ID	CHEBI:27779
ChEBI Name	griseofulvin
Stars
Definition	An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.
Secondary ChEBI IDs	CHEBI:5546, CHEBI:24429
Last Modified	30 August 2022
Downloads	Molfile

Formula	C17H17ClO6
Net Charge	0
Average Mass	352.770
Monoisotopic Mass	352.07137
SMILES	COC1=CC(=O)C[C@@H](C)[C@]12Oc1c(Cl)c(OC)cc(OC)c1C2=O
InChI	InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
InChIKey	DDUHZTYCFQRHIY-RBHXEPJQSA-N

Wikipedia

Roles Classification

antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria.

Penicillium metabolite Any fungal metabolite produced during a metabolic reaction in Penicillium.

antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals.

antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.

antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals.

antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.

antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases.

antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals.

ChEBI Ontology

Outgoing Relation(s)
	griseofulvin (CHEBI:27779) has role Penicillium metabolite (CHEBI:76964)
	griseofulvin (CHEBI:27779) has role antibacterial agent (CHEBI:33282)
	griseofulvin (CHEBI:27779) has role antiinfective agent (CHEBI:35441)
	griseofulvin (CHEBI:27779) is a 1-benzofurans (CHEBI:38830)
	griseofulvin (CHEBI:27779) is a antibiotic antifungal drug (CHEBI:87113)
	griseofulvin (CHEBI:27779) is a benzofuran antifungal drug (CHEBI:87128)
	griseofulvin (CHEBI:27779) is a organochlorine compound (CHEBI:36683)
	griseofulvin (CHEBI:27779) is a oxaspiro compound (CHEBI:37948)

IUPAC Name
(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione

UniProt Name	Source
griseofulvin	UniProt

Citations