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CHEBI:27690 - acetazolamide
| Formula | C4H6N4O3S2 |
| Net Charge | 0 |
| Average Mass | 222.251 |
| Monoisotopic Mass | 221.98813 |
| SMILES | CC(=O)Nc1nnc(S(N)(=O)=O)s1 |
| InChI | InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) |
| InChIKey | BZKPWHYZMXOIDC-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | EC 4.2.1.1 (carbonic anhydrase) inhibitor An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antiglaucoma drug Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye. hypoglycemic agent A drug which lowers the blood glucose level. anticonvulsant A drug used to prevent seizures or reduce their severity. renoprotective agent Any compound that is able to prevent damage to the kidneys. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. diuretic An agent that promotes the excretion of urine through its effects on kidney function. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. vasoconstrictor agent Drug used to cause constriction of the blood vessels. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| acetazolamide (CHEBI:27690) has parent hydride 1,3,4-thiadiazole (CHEBI:39472) |
| acetazolamide (CHEBI:27690) has role analgesic (CHEBI:35480) |
| acetazolamide (CHEBI:27690) has role antibacterial agent (CHEBI:33282) |
| acetazolamide (CHEBI:27690) has role anticonvulsant (CHEBI:35623) |
| acetazolamide (CHEBI:27690) has role antiglaucoma drug (CHEBI:39456) |
| acetazolamide (CHEBI:27690) has role antihypertensive agent (CHEBI:35674) |
| acetazolamide (CHEBI:27690) has role antineoplastic agent (CHEBI:35610) |
| acetazolamide (CHEBI:27690) has role antipsychotic agent (CHEBI:35476) |
| acetazolamide (CHEBI:27690) has role cardiovascular drug (CHEBI:35554) |
| acetazolamide (CHEBI:27690) has role diuretic (CHEBI:35498) |
| acetazolamide (CHEBI:27690) has role EC 4.2.1.1 (carbonic anhydrase) inhibitor (CHEBI:23018) |
| acetazolamide (CHEBI:27690) has role hypoglycemic agent (CHEBI:35526) |
| acetazolamide (CHEBI:27690) has role immunosuppressive agent (CHEBI:35705) |
| acetazolamide (CHEBI:27690) has role ophthalmology drug (CHEBI:66981) |
| acetazolamide (CHEBI:27690) has role renoprotective agent (CHEBI:231911) |
| acetazolamide (CHEBI:27690) has role vasoconstrictor agent (CHEBI:50514) |
| acetazolamide (CHEBI:27690) is a monocarboxylic acid amide (CHEBI:29347) |
| acetazolamide (CHEBI:27690) is a sulfonamide (CHEBI:35358) |
| acetazolamide (CHEBI:27690) is a thiadiazoles (CHEBI:38099) |
| acetazolamide (CHEBI:27690) is conjugate acid of acetazolamide(1−) (CHEBI:50634) |
| Incoming Relation(s) |
| acetazolamide sodium (CHEBI:31163) has part acetazolamide (CHEBI:27690) |
| acetazolamide(1−) (CHEBI:50634) is conjugate base of acetazolamide (CHEBI:27690) |
| IUPAC Name |
|---|
| N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide |
| INNs | Source |
|---|---|
| acetazolamida | ChemIDplus |
| acétazolamide | ChEBI |
| acetazolamidum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide | NIST Chemistry WebBook |
| 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | PDBeChem |
| 5-acetylamino-1,3,4-thiadiazole-2-sulfonamide | ChEBI |
| Acetazolamide | KEGG COMPOUND |
| Atenezo | ChEMBL |
| Diamox | ChemIDplus |
| Brand Names | Source |
|---|---|
| Defiltran | DrugBank |
| Diacarb | DrugBank |
| Diamox sr | ChEMBL |
| Diluran | DrugBank |
| Eytazox | ChEMBL |
| Glaupax | DrugBank |
| Citations |
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