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CHEBI:2674 - amodiaquine
| Formula | C20H22ClN3O |
| Net Charge | 0 |
| Average Mass | 355.869 |
| Monoisotopic Mass | 355.14514 |
| SMILES | CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O |
| InChI | InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23) |
| InChIKey | OVCDSSHSILBFBN-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | drug allergen Any drug which causes the onset of an allergic reaction. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. EC 2.1.1.8 (histamine N-methyltransferase) inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of histamine N-methyltransferase (EC 2.1.1.8). antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| Applications: | drug allergen Any drug which causes the onset of an allergic reaction. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| amodiaquine (CHEBI:2674) has role anticoronaviral agent (CHEBI:149553) |
| amodiaquine (CHEBI:2674) has role antimalarial (CHEBI:38068) |
| amodiaquine (CHEBI:2674) has role drug allergen (CHEBI:88188) |
| amodiaquine (CHEBI:2674) has role EC 2.1.1.8 (histamine N-methyltransferase) inhibitor (CHEBI:110725) |
| amodiaquine (CHEBI:2674) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| amodiaquine (CHEBI:2674) has role prodrug (CHEBI:50266) |
| amodiaquine (CHEBI:2674) is a aminoquinoline (CHEBI:36709) |
| amodiaquine (CHEBI:2674) is a organochlorine compound (CHEBI:36683) |
| amodiaquine (CHEBI:2674) is a phenols (CHEBI:33853) |
| amodiaquine (CHEBI:2674) is a secondary amino compound (CHEBI:50995) |
| amodiaquine (CHEBI:2674) is a tertiary amino compound (CHEBI:50996) |
| amodiaquine (CHEBI:2674) is conjugate base of amodiaquine(1+) (CHEBI:131327) |
| Incoming Relation(s) |
| amodiaquine hydrochloride (CHEBI:50652) has part amodiaquine (CHEBI:2674) |
| amodiaquine(1+) (CHEBI:131327) is conjugate acid of amodiaquine (CHEBI:2674) |
| IUPAC Name |
|---|
| 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol |
| INNs | Source |
|---|---|
| amodiaquina | ChemIDplus |
| amodiaquine | ChEBI |
| amodiaquinum | ChemIDplus |
| Synonym | Source |
|---|---|
| Amodiaquine | KEGG COMPOUND |
| Citations |
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