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CHEBI:2674 - amodiaquine
| Formula | C20H22ClN3O |
| Net Charge | 0 |
| Average Mass | 355.869 |
| Monoisotopic Mass | 355.14514 |
| SMILES | CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O |
| InChI | InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23) |
| InChIKey | OVCDSSHSILBFBN-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. drug allergen Any drug which causes the onset of an allergic reaction. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. EC 2.1.1.8 (histamine N-methyltransferase) inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of histamine N-methyltransferase (EC 2.1.1.8). |
| Applications: | prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. drug allergen Any drug which causes the onset of an allergic reaction. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| amodiaquine (CHEBI:2674) has role anticoronaviral agent (CHEBI:149553) |
| amodiaquine (CHEBI:2674) has role antimalarial (CHEBI:38068) |
| amodiaquine (CHEBI:2674) has role drug allergen (CHEBI:88188) |
| amodiaquine (CHEBI:2674) has role EC 2.1.1.8 (histamine N-methyltransferase) inhibitor (CHEBI:110725) |
| amodiaquine (CHEBI:2674) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| amodiaquine (CHEBI:2674) has role prodrug (CHEBI:50266) |
| amodiaquine (CHEBI:2674) is a aminoquinoline (CHEBI:36709) |
| amodiaquine (CHEBI:2674) is a organochlorine compound (CHEBI:36683) |
| amodiaquine (CHEBI:2674) is a phenols (CHEBI:33853) |
| amodiaquine (CHEBI:2674) is a secondary amino compound (CHEBI:50995) |
| amodiaquine (CHEBI:2674) is a tertiary amino compound (CHEBI:50996) |
| amodiaquine (CHEBI:2674) is conjugate base of amodiaquine(1+) (CHEBI:131327) |
| Incoming Relation(s) |
| amodiaquine hydrochloride (CHEBI:50652) has part amodiaquine (CHEBI:2674) |
| amodiaquine(1+) (CHEBI:131327) is conjugate acid of amodiaquine (CHEBI:2674) |
| IUPAC Name |
|---|
| 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol |
| INNs | Source |
|---|---|
| amodiaquina | ChemIDplus |
| amodiaquine | ChEBI |
| amodiaquinum | ChemIDplus |
| Synonym | Source |
|---|---|
| Amodiaquine | KEGG COMPOUND |
| Citations |
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