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CHEBI:2637 - amikacin
| Formula | C22H43N5O13 |
| Net Charge | 0 |
| Average Mass | 585.608 |
| Monoisotopic Mass | 585.28574 |
| SMILES | NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O |
| InChI | InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1 |
| InChIKey | LKCWBDHBTVXHDL-RMDFUYIESA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. nephrotoxic agent A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antibacterial drug A drug used to treat or prevent bacterial infections. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Applications: | antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antibacterial drug A drug used to treat or prevent bacterial infections. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| amikacin (CHEBI:2637) has functional parent kanamycin A (CHEBI:17630) |
| amikacin (CHEBI:2637) has role antibacterial agent (CHEBI:33282) |
| amikacin (CHEBI:2637) has role antibacterial drug (CHEBI:36047) |
| amikacin (CHEBI:2637) has role antiinfective agent (CHEBI:35441) |
| amikacin (CHEBI:2637) has role antimicrobial agent (CHEBI:33281) |
| amikacin (CHEBI:2637) has role antimicrobial agent (CHEBI:33281) |
| amikacin (CHEBI:2637) has role antitubercular agent (CHEBI:33231) |
| amikacin (CHEBI:2637) has role nephrotoxic agent (CHEBI:50909) |
| amikacin (CHEBI:2637) has role ophthalmology drug (CHEBI:66981) |
| amikacin (CHEBI:2637) is a amino cyclitol glycoside (CHEBI:22479) |
| amikacin (CHEBI:2637) is a aminoglycoside (CHEBI:47779) |
| amikacin (CHEBI:2637) is a carboxamide (CHEBI:37622) |
| amikacin (CHEBI:2637) is a α-D-glucoside (CHEBI:22390) |
| amikacin (CHEBI:2637) is conjugate base of amikacin(4+) (CHEBI:84739) |
| Incoming Relation(s) |
| amikacin(4+) (CHEBI:84739) is conjugate acid of amikacin (CHEBI:2637) |
| IUPAC Name |
|---|
| (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-α-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-α-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide |
| INNs | Source |
|---|---|
| amikacin | ChemIDplus |
| amikacina | ChemIDplus |
| amikacine | ChemIDplus |
| amikacinum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A | ChemIDplus |
| Amikacin | KEGG COMPOUND |
| BAY 41-6551 | ChEMBL |
| O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→4)-O-(6-amino-6-deoxy-α-D-glucopyranosyl-(1→6))-N3-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine | ChemIDplus |
| NSC-177001 | ChEMBL |
| Potentox | ChEMBL |
| Brand Names | Source |
|---|---|
| Amicacin | DrugBank |
| Amiglyde-V | DrugBank |
| Amikavet | DrugBank |
| Briclin | DrugBank |
| Citations |
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