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CHEBI:2628 - ambenonium chloride

Default Structure
ChEBI IDCHEBI:2628
ChEBI Nameambenonium chloride
Stars
DefinitionA symmetrical oxalamide-based bis-quaternary ammonium salt having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
Last Modified8 July 2025
DownloadsMolfile
FormulaC28H42Cl2N4O2.2Cl
Net Charge0
Average Mass608.482
Monoisotopic Mass606.20619
SMILESCC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)Cc1ccccc1Cl)Cc1ccccc1Cl.[Cl-].[Cl-]
InChIInChI=1S/C28H40Cl2N4O2.2ClH/c1-5-33(6-2,21-23-13-9-11-15-25(23)29)19-17-31-27(35)28(36)32-18-20-34(7-3,8-4)22-24-14-10-12-16-26(24)30;;/h9-16H,5-8,17-22H2,1-4H3;2*1H
InChIKeyDXUUXWKFVDVHIK-UHFFFAOYSA-N
Roles Classification
Biological Roles:
EC 3.1.1.8 (cholinesterase) inhibitor  An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
neurotransmitter agent  A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
Application:
neurotransmitter agent  A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
ChEBI Ontology
Outgoing Relation(s)
ambenonium chloride (CHEBI:2628) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
ambenonium chloride (CHEBI:2628) has role neurotransmitter agent (CHEBI:35942)
ambenonium chloride (CHEBI:2628) is a organic chloride salt (CHEBI:36094)
ambenonium chloride (CHEBI:2628) is a quaternary ammonium salt (CHEBI:35273)
IUPAC Name 
2,2'-[(1,2-dioxoethane-1,2-diyl)diimino]bis[N-(2-chlorobenzyl)-N,N-diethylethanaminium] dichloride
INNs  Source
ambenonii chloridumChemIDplus
ambenonium chlorideKEGG DRUG
Chlorure d'ambenoniumChemIDplus
Cloruro de ambenonioChemIDplus
Synonyms  Source
Ambenonium dichlorideChemIDplus
Ambestigmin chlorideChemIDplus
N,N'-Bis(2-diethylaminoethyl)oxamide bis(2-chlorobenzyl chloride)ChemIDplus
(Oxalylbis(iminoethylene))bis((o-chlorobenzyl)diethylammonium) dichlorideChemIDplus
Manual XrefsDatabases
D01001KEGG DRUG
DB01122DrugBank
DE1024517Patent
Registry NumbersSources
Beilstein:7563564Beilstein
CAS:115-79-7ChemIDplus
Citations