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CHEBI:2618 - amantadine
| Formula | C10H17N |
| Net Charge | 0 |
| Average Mass | 151.253 |
| Monoisotopic Mass | 151.13610 |
| SMILES | NC12CC3CC(CC(C3)C1)C2 |
| InChI | InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2 |
| InChIKey | DKNWSYNQZKUICI-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. antiviral agent A substance that destroys or inhibits replication of viruses. NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antiviral drug A substance used in the prophylaxis or therapy of virus diseases. dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. antiparkinson drug A drug used in the treatment of Parkinson's disease. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. hypoglycemic agent A drug which lowers the blood glucose level. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| amantadine (CHEBI:2618) has parent hydride adamantane (CHEBI:40519) |
| amantadine (CHEBI:2618) has role analgesic (CHEBI:35480) |
| amantadine (CHEBI:2618) has role antiinfective agent (CHEBI:35441) |
| amantadine (CHEBI:2618) has role antiparkinson drug (CHEBI:48407) |
| amantadine (CHEBI:2618) has role antipsychotic agent (CHEBI:35476) |
| amantadine (CHEBI:2618) has role antiviral agent (CHEBI:22587) |
| amantadine (CHEBI:2618) has role antiviral drug (CHEBI:36044) |
| amantadine (CHEBI:2618) has role dopaminergic agent (CHEBI:48560) |
| amantadine (CHEBI:2618) has role hypoglycemic agent (CHEBI:35526) |
| amantadine (CHEBI:2618) has role immunosuppressive agent (CHEBI:35705) |
| amantadine (CHEBI:2618) has role neuroprotective agent (CHEBI:63726) |
| amantadine (CHEBI:2618) has role NMDA receptor antagonist (CHEBI:60643) |
| amantadine (CHEBI:2618) has role non-narcotic analgesic (CHEBI:35481) |
| amantadine (CHEBI:2618) is a adamantanes (CHEBI:51339) |
| amantadine (CHEBI:2618) is a primary aliphatic amine (CHEBI:17062) |
| amantadine (CHEBI:2618) is conjugate base of adamantan-1-aminium (CHEBI:48320) |
| Incoming Relation(s) |
| adamantan-1-aminium (CHEBI:48320) is conjugate acid of amantadine (CHEBI:2618) |
| IUPAC Name |
|---|
| adamantan-1-ylamine |
| INNs | Source |
|---|---|
| amantadina | ChemIDplus |
| amantadine | ChemIDplus |
| amantadinum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-adamantanamine | NIST Chemistry WebBook |
| 1-adamantylamine | ChEBI |
| 1-aminoadamantane | ChEBI |
| Amantadine | KEGG COMPOUND |
| Amantidine | DrugBank |
| Aminoadamantane | DrugBank |
| Brand Names | Source |
|---|---|
| Viregyt | ChemIDplus |
| Virosol | ChemIDplus |
| Citations |
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