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CHEBI:234592 - Iadademstat

Default Structure
ChEBI IDCHEBI:234592
ChEBI NameIadademstat
Stars
DefinitionORY-1001 2HCl is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 below 20 nM, with high selectivity against related FAD dependent aminoxidases. Iadademstat is highly potent, orally active, and has antileukemic activity. Iadademstat can be used for relapsed or refractory acute myeloid leukemia research.
Submitteraxiao
DownloadsMolfile
FormulaC15H22N2
Net Charge0
Average Mass230.355
Monoisotopic Mass230.17830
SMILES[H][C@]1(N[C@@H]2C[C@H]2c2ccccc2)CC[C@H](N)CC1
InChIInChI=1S/C15H22N2/c16-12-6-8-13(9-7-12)17-15-10-14(15)11-4-2-1-3-5-11/h1-5,12-15,17H,6-10,16H2/t12-,13-,14-,15+/m0/s1
InChIKeyALHBJBCQLJZYON-ZQDZILKHSA-N
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
Iadademstat (CHEBI:234592) has role antineoplastic agent (CHEBI:35610)
Iadademstat (CHEBI:234592) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
IadademstatChEMBL
ORY-1001SUBMITTER
RG-6016ChEMBL
Registry NumbersSources
CAS:1431304-21-0SUBMITTER
Citations