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CHEBI:234433 - (R)-norketamine

ChEBI IDCHEBI:234433
ChEBI Name(R)-norketamine
Stars
ASCII Name(R)-norketamine
DefinitionThe (R)-enantiomer of norketamine.
Last Modified10 June 2025
SubmitterAdnan
DownloadsMolfile
FormulaC12H14ClNO
Net Charge0
Average Mass223.703
Monoisotopic Mass223.07639
SMILESN[C@@]1(c2ccccc2Cl)CCCCC1=O
InChIInChI=1S/C12H14ClNO/c13-10-6-2-1-5-9(10)12(14)8-4-3-7-11(12)15/h1-2,5-6H,3-4,7-8,14H2/t12-/m1/s1
InChIKeyBEQZHFIKTBVCAU-GFCCVEGCSA-N
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
antinociceptive agent  Any agent that inhibits nociception.
human xenobiotic metabolite  Any human metabolite produced by metabolism of a xenobiotic compound in humans.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
NMDA receptor antagonist  Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
nicotinic antagonist  An antagonist at the nicotinic cholinergic receptor.
Applications:
antinociceptive agent  Any agent that inhibits nociception.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
nicotinic antagonist  An antagonist at the nicotinic cholinergic receptor.
ChEBI Ontology
Outgoing Relation(s)
(R)-norketamine (CHEBI:234433) is a norketamine (CHEBI:91519)
(R)-norketamine (CHEBI:234433) is enantiomer of (S)-norketamine (CHEBI:234434)
Incoming Relation(s)
(S)-norketamine (CHEBI:234434) is enantiomer of (R)-norketamine (CHEBI:234433)
IUPAC Name 
(2R)-2-amino-2-(2-chlorophenyl)cyclohexanone
Synonyms  Source
(2R)-2-amino-2-(2-chlorophenyl)cyclohexan-1-oneIUPAC
R-norketamineChEBI
(R)-2-amino-2-(2-chlorophenyl)cyclohexanoneChEBI
(+)-norketamineChEBI
N-demethyl-(R)-(+)-ketamineChEBI
(R)-2-(2-chlorophenyl)-2-aminocyclohexanoneChEBI
Registry NumbersSources
CAS:83777-64-4ChEBI
Citations