tebanicline (CHEBI:234304)

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CHEBI:234304 - tebanicline

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ChEBI ID	CHEBI:234304
ChEBI Name	tebanicline
Stars
Definition	A monochloropyridine that is 2-chloropyridine substituted by a (2R)-azetidin-2-ylmethoxy group at position 5. It is a potent nicotinic acetylcholine receptor agonist with analgesic and antinociceptive properties.
Last Modified	15 May 2025
Submitter	sbalu
Downloads	Molfile

Formula	C9H11ClN2O
Net Charge	0
Average Mass	198.653
Monoisotopic Mass	198.05599
SMILES	Clc1ccc(OC[C@H]2CCN2)cn1
InChI	InChI=1S/C9H11ClN2O/c10-9-2-1-8(5-12-9)13-6-7-3-4-11-7/h1-2,5,7,11H,3-4,6H2/t7-/m1/s1
InChIKey	MKTAGSRKQIGEBH-SSDOTTSWSA-N

Wikipedia

Roles Classification

Biological Roles:	antinociceptive agent Any agent that inhibits nociception. nicotinic acetylcholine receptor agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:	antinociceptive agent Any agent that inhibits nociception. nicotinic acetylcholine receptor agonist An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.

ChEBI Ontology

Outgoing Relation(s)
	tebanicline (CHEBI:234304) has role antinociceptive agent (CHEBI:228138)
	tebanicline (CHEBI:234304) has role nicotinic acetylcholine receptor agonist (CHEBI:47958)
	tebanicline (CHEBI:234304) has role non-narcotic analgesic (CHEBI:35481)
	tebanicline (CHEBI:234304) is a aromatic ether (CHEBI:35618)
	tebanicline (CHEBI:234304) is a azetidines (CHEBI:38777)
	tebanicline (CHEBI:234304) is a monochloropyridine (CHEBI:39172)

IUPAC Name
5-[(2R)-azetidin-2-ylmethoxy]-2-chloropyridine

INNs	Source
tebanicline	WHO MedNet
tebaniclinum	WHO MedNet
tébanicline	WHO MedNet
tebaniclina	WHO MedNet

Synonyms	Source
ABT594	ChEBI
ABT-594	ChEBI
ABT 594	ChEBI
5-[(2R)-2-azetidinylmethoxy]-2-chloropyridine	ChEBI
(R)-5-(azetidin-2-ylmethoxy)-2-chloropyridine	ChEBI
5-[((2R)-azetidin-2-yl)methoxy]-2-chloropyridine	ChEBI

Manual Xrefs	Databases
Tebanicline	Wikipedia
WO9953922	Patent

Registry Numbers	Sources
CAS:198283-73-7	ChEBI

Citations