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CHEBI:234264 - TTK21

ChEBI IDCHEBI:234264
ChEBI NameTTK21
Stars
DefinitionA secondary carboxamide resulting from the formal condensation of the carboxy group of 2-propoxybenzoic acid with the amino group of 4-chloro-3-(trifluoromethyl)aniline. It is an activator of the histone acetyltransferases CBP/p300 that passes the blood-brain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanospheres.
Last Modified19 May 2025
Submitteraxiao
DownloadsMolfile
FormulaC17H15ClF3NO2
Net Charge0
Average Mass357.759
Monoisotopic Mass357.07434
SMILESCCCOc1ccccc1C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1
InChIInChI=1S/C17H15ClF3NO2/c1-2-9-24-15-6-4-3-5-12(15)16(23)22-11-7-8-14(18)13(10-11)17(19,20)21/h3-8,10H,2,9H2,1H3,(H,22,23)
InChIKeyAQJBXYBDNZHZRE-UHFFFAOYSA-N
Roles Classification
Biological Role:
histone acetyltransferase activator  Any compound that binds to and activates the enzyme histone acetyltransferase (EC 2.3.1.48).
Application:
nootropic agent  Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
ChEBI Ontology
Outgoing Relation(s)
TTK21 (CHEBI:234264) has role histone acetyltransferase activator (CHEBI:90374)
TTK21 (CHEBI:234264) has role nootropic agent (CHEBI:66980)
TTK21 (CHEBI:234264) is a (trifluoromethyl)benzenes (CHEBI:83565)
TTK21 (CHEBI:234264) is a aromatic ether (CHEBI:35618)
TTK21 (CHEBI:234264) is a benzamides (CHEBI:22702)
TTK21 (CHEBI:234264) is a monochlorobenzenes (CHEBI:83403)
TTK21 (CHEBI:234264) is a secondary carboxamide (CHEBI:140325)
IUPAC Name 
N-[4-chloro-3-(trifluoromethyl)phenyl]-2-propoxybenzamide
Synonyms  Source
TTK 21SUBMITTER
TTK-21ChEBI
Registry NumbersSources
CAS:709676-56-2ChEBI
Citations