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CHEBI:234044 - barbital sodium
| Formula | C8H11N2O3.Na |
| Net Charge | 0 |
| Average Mass | 206.177 |
| Monoisotopic Mass | 206.06674 |
| SMILES | CCC1(CC)C([O-])=NC(=O)N=C1O.[Na+] |
| InChI | InChI=1S/C8H12N2O3.Na/c1-3-8(4-2)5(11)9-7(13)10-6(8)12;/h3-4H2,1-2H3,(H2,9,10,11,12,13);/q;+1/p-1 |
| InChIKey | RGHFKWPGWBFQLN-UHFFFAOYSA-M |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | anticonvulsant A drug used to prevent seizures or reduce their severity. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| barbital sodium (CHEBI:234044) has role anticonvulsant (CHEBI:35623) |
| barbital sodium (CHEBI:234044) is a barbiturates (CHEBI:22693) |
| IUPAC Name |
|---|
| sodium;5,5-diethyl-4,6-dioxo-1H-pyrimidin-2-olate |
| Registry Numbers | Sources |
|---|---|
| CAS:144-02-5 | SUBMITTER |
| Citations |
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