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CHEBI:233985 - RTI-83

Default Structure
ChEBI IDCHEBI:233985
ChEBI NameRTI-83
Stars
SubmitterFlyBase
DownloadsMolfile
FormulaC18H25NO2
Net Charge0
Average Mass287.403
Monoisotopic Mass287.18853
SMILES[H][C@@]12CC[C@@]([H])(N1C)[C@@]([H])(C(=O)OC)[C@@]([H])(c1ccc(CC)cc1)C2
InChIInChI=1S/C18H25NO2/c1-4-12-5-7-13(8-6-12)15-11-14-9-10-16(19(14)2)17(15)18(20)21-3/h5-8,14-17H,4,9-11H2,1-3H3/t14-,15+,16+,17-/m0/s1
InChIKeyUAMCGXVVAUEEEU-HZMVEIRTSA-N
Wikipedia
Roles Classification
Biological Roles:
serotonin uptake inhibitor  A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
Applications:
serotonin uptake inhibitor  A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
ChEBI Ontology
Outgoing Relation(s)
RTI-83 (CHEBI:233985) has role dopamine uptake inhibitor (CHEBI:51039)
RTI-83 (CHEBI:233985) has role serotonin uptake inhibitor (CHEBI:50949)
RTI-83 (CHEBI:233985) is a organic molecular entity (CHEBI:50860)
IUPAC Name 
methyl (1R,2S,3S,5S)-3-(4-ethylphenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Synonym  Source
(-)-2β-carbomethoxy-3β-(4-ethylphenyl)tropaneSUBMITTER
Manual XrefsDatabases
https://en.wikipedia.org/wiki/RTI-83Wikipedia
Registry NumbersSources
CAS:155337-52-3SUBMITTER
Citations