CHEBI:233585 - BAM15

ChEBI IDCHEBI:233585
ChEBI NameBAM15
Stars
DefinitionAn organic heterobicyclic compound that is [1,2,5]oxadiazolo[3,4-b]pyrazine substituted by (2-fluorophenyl)amino groups at positions 5 and 6. It is a mitochondrial protonophore uncoupler that is a potential treatment for obesity and sepsis.
Last Modified2 April 2025
SubmitterFlyBase
DownloadsMolfile
FormulaC16H10F2N6O
Net Charge0
Average Mass340.293
Monoisotopic Mass340.08842
SMILESFc1ccccc1Nc1nc2nonc2nc1Nc1ccccc1F
InChIInChI=1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24)
InChIKeyOEGJBRZAJRPPHL-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
anti-obesity agent  Any substance which is used to reduce or control weight.
Applications:
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
antiparasitic agent  A substance used to treat or prevent parasitic infections.
ChEBI Ontology
Outgoing Relation(s)
BAM15 (CHEBI:233585) has role anti-inflammatory agent (CHEBI:67079)
BAM15 (CHEBI:233585) has role anti-obesity agent (CHEBI:74518)
BAM15 (CHEBI:233585) has role antineoplastic agent (CHEBI:35610)
BAM15 (CHEBI:233585) has role antiparasitic agent (CHEBI:35442)
BAM15 (CHEBI:233585) has role apoptosis inducer (CHEBI:68495)
BAM15 (CHEBI:233585) has role geroprotector (CHEBI:176497)
BAM15 (CHEBI:233585) has role renoprotective agent (CHEBI:231911)
BAM15 (CHEBI:233585) is a monofluorobenzenes (CHEBI:83575)
BAM15 (CHEBI:233585) is a organic heterobicyclic compound (CHEBI:27171)
BAM15 (CHEBI:233585) is a secondary amino compound (CHEBI:50995)
BAM15 (CHEBI:233585) is a substituted aniline (CHEBI:48975)
IUPAC Name 
N,N'-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
Synonyms  Source
5-N,6-N-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamineChEBI
N5,N6-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamineIUPAC
BAM 15ChEBI
BAM-15ChEBI
Manual XrefsDatabases
BAM15Wikipedia
Registry NumbersSources
CAS:210302-17-3SUBMITTER
Citations