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CHEBI:233415 - Pf-06840003

Default Structure
ChEBI IDCHEBI:233415
ChEBI NamePf-06840003
Stars
DefinitionIDO1 Inhibitor PF-06840003 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities. Upon administration, IDO1 inhibitor PF-06840003 targets and binds to IDO1, an enzyme responsible for the oxidation of tryptophan into kynurenine.
Submitterlbonaobra
DownloadsMolfile
FormulaC12H9FN2O2
Net Charge0
Average Mass232.214
Monoisotopic Mass232.06481
SMILESO=C1CC(c2cnc3ccc(F)cc23)C(=O)N1
InChIInChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17)
InChIKeyMXKLDYKORJEOPR-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
Pf-06840003 (CHEBI:233415) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
198474-05-4SUBMITTER
3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dioneSUBMITTER
Registry NumbersSources
CAS:198474-05-4SUBMITTER