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CHEBI:233412 - Ponesimod

Default Structure
ChEBI IDCHEBI:233412
ChEBI NamePonesimod
Stars
DefinitionPonesimod is a Sphingosine 1-phosphate Receptor Modulator. The mechanism of action of ponesimod is as a Sphingosine 1-Phosphate Receptor Modulator.
Submitterlbonaobra
DownloadsMolfile
FormulaC23H25ClN2O4S
Net Charge0
Average Mass460.983
Monoisotopic Mass460.12236
SMILESCCC/N=C1\S/C(=C\c2ccc(OC[C@H](O)CO)c(Cl)c2)C(=O)N1c1ccccc1C
InChIInChI=1S/C23H25ClN2O4S/c1-3-10-25-23-26(19-7-5-4-6-15(19)2)22(29)21(31-23)12-16-8-9-20(18(24)11-16)30-14-17(28)13-27/h4-9,11-12,17,27-28H,3,10,13-14H2,1-2H3/b21-12-,25-23-/t17-/m1/s1
InChIKeyLPAUOXUZGSBGDU-STDDISTJSA-N
Roles Classification
Biological Role:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Applications:
antipsoriatic  A drug used to treat psoriasis.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
ChEBI Ontology
Outgoing Relation(s)
Ponesimod (CHEBI:233412) has role antipsoriatic (CHEBI:50748)
Ponesimod (CHEBI:233412) has role immunosuppressive agent (CHEBI:35705)
Ponesimod (CHEBI:233412) is a aromatic ether (CHEBI:35618)
Ponesimod (CHEBI:233412) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
(5Z)-5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylidene]-3-(2-methylphenyl)-2-propylimino-1,3-thiazolidin-4-oneSUBMITTER
854107-55-4SUBMITTER
ACT-128800ChEMBL
PonesimodChEMBL
Brand Name  Source
PonvoryChEMBL
Registry NumbersSources
CAS:854107-55-4SUBMITTER
Citations