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CHEBI:233411 - Zotiraciclib

Default Structure
ChEBI IDCHEBI:233411
ChEBI NameZotiraciclib
Stars
DefinitionZotiraciclib (SB1317; TG02) is a novel small molecule potent CDK/JAK2/FLT3 inhibitor, emerged with potent CDK (IC50 against CDKs 1, 2 and 9 = 9, 5 and 3 nM, respectively), FLT3 (IC50 = 19 nM) and JAK2 (IC50 = 19 nM) potency.
Submitterlbonaobra
DownloadsMolfile
FormulaC23H24N4O
Net Charge0
Average Mass372.472
Monoisotopic Mass372.19501
SMILES[H]/C1=C(\[H])CN(C)Cc2cccc(c2)Nc2nccc(n2)-c2cccc(c2)OCC1
InChIInChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26)/b3-2-
InChIKeyVXBAJLGYBMTJCY-IHWYPQMZSA-N
ChEBI Ontology
Outgoing Relation(s)
Zotiraciclib (CHEBI:233411) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
(16E)-14-methyl-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8,10,12(26),16,21,23-decaeneSUBMITTER
937270-47-8SUBMITTER
SB1317SUBMITTER
TG-02SUBMITTER
Registry NumbersSources
CAS:937270-47-8SUBMITTER