EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:233324 - Darovasertib

Default Structure
ChEBI IDCHEBI:233324
ChEBI NameDarovasertib
Stars
DefinitionDarovasertib is an orally available protein kinase C (PKC) inhibitor with potential immunosuppressive and antineoplastic activities. Upon oral administration, darovasertib inds to and inhibits PKC, which prevents the activation of PKC-mediated signaling pathways. This may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor cells.
Submitterlbonaobra
DownloadsMolfile
FormulaC22H23F3N8O
Net Charge0
Average Mass472.475
Monoisotopic Mass472.19469
SMILESCC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3ncccc3C(F)(F)F)cnc2N)CC1
InChIInChI=1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23,24)25)4-2-8-28-16/h2-5,8-9,12H,6-7,10-11,27H2,1H3,(H2,26,30)(H,29,32,34)
InChIKeyXXJXHXJWQSCNPX-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
Darovasertib (CHEBI:233324) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
1874276-76-2SUBMITTER
3-amino-N-[3-(4-amino-4-methylpiperidin-1-yl)pyridin-2-yl]-6-[3-(trifluoromethyl)pyridin-2-yl]pyrazine-2-carboxamideSUBMITTER
IDE196SUBMITTER
Registry NumbersSources
CAS:1874276-76-2SUBMITTER