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CHEBI:233155 - 3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide

ChEBI IDCHEBI:233155
ChEBI Name3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide
Stars
DefinitionA member of the class of thiophenes that is thiophene substituted by aminocarbonyl, amino, and 4-methoxyphenyl groups at positions 2, 3, and 5, respectively. It is a small-molecule activator of Nav 1.1 channels.
Last Modified21 May 2025
Submitterdoughowe
DownloadsMolfile
FormulaC12H12N2O2S
Net Charge0
Average Mass248.307
Monoisotopic Mass248.06195
SMILESCOc1ccc(-c2cc(N)c(C(N)=O)s2)cc1
InChIInChI=1S/C12H12N2O2S/c1-16-8-4-2-7(3-5-8)10-6-9(13)11(17-10)12(14)15/h2-6H,13H2,1H3,(H2,14,15)
InChIKeyOEUITKOCUWEFOB-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
Application:
anticonvulsant  A drug used to prevent seizures or reduce their severity.
ChEBI Ontology
Outgoing Relation(s)
3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide (CHEBI:233155) has role anticonvulsant (CHEBI:35623)
3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide (CHEBI:233155) has role sodium channel modulator (CHEBI:39000)
3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide (CHEBI:233155) is a aromatic amine (CHEBI:33860)
3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide (CHEBI:233155) is a monomethoxybenzene (CHEBI:25235)
3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide (CHEBI:233155) is a primary carboxamide (CHEBI:140324)
3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide (CHEBI:233155) is a thiophenes (CHEBI:26961)
IUPAC Name 
3-amino-5-(4-methoxyphenyl)thiophene-2-carboxamide
Synonym  Source
AA43279SUBMITTER
Registry NumbersSources
CAS:354812-16-1ChEBI
Citations