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CHEBI:232994 - Prochlorperazine Edisylate

Default Structure
ChEBI IDCHEBI:232994
ChEBI NameProchlorperazine Edisylate
Stars
DefinitionProchlorperazine Edisylate is the edisylate salt form of prochlorperazine, a derivative of phenothiazine with antipsychotic and antiemetic properties. Prochlorperazine edisylate blocks postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, including hallucinations and delusions. Prochlorperazine edisylate appears to exert its antiemetic activity by blocking the dopamine and histamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting.
Submitterruixy
DownloadsMolfile
FormulaC20H24ClN3S.C2H6O6S2
Net Charge0
Average Mass564.151
Monoisotopic Mass563.09853
SMILESCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1.O=S(=O)(O)CCS(=O)(=O)O
InChIInChI=1S/C20H24ClN3S.C2H6O6S2/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;3-9(4,5)1-2-10(6,7)8/h2-3,5-8,15H,4,9-14H2,1H3;1-2H2,(H,3,4,5)(H,6,7,8)
InChIKeySWOUGRBFXFILIB-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
Prochlorperazine Edisylate (CHEBI:232994) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acidSUBMITTER
prochlorperazine ethanedisulfonateSUBMITTER
Prochlorperazine ethane disulfonateSUBMITTER
Registry NumbersSources
CAS:1257-78-9SUBMITTER