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CHEBI:232993 - Primaquine Phosphate

Default Structure
ChEBI IDCHEBI:232993
ChEBI NamePrimaquine Phosphate
Stars
DefinitionPrimaquine Phosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue (exo-erythrocytic) malarial infection, preventing the development of the erythrocytic forms of the parasite which are responsible for relapses in Plasmodium vivax and ovale malaria. Primaquine is active against late hepatic stages (hypnozoites, schizonts).
Submitterruixy
DownloadsMolfile
FormulaC15H21N3O.2H3O4P
Net Charge0
Average Mass455.341
Monoisotopic Mass455.12225
SMILESCOc1cc(NC(C)CCCN)c2ncccc2c1.O=P(O)(O)O.O=P(O)(O)O
InChIInChI=1S/C15H21N3O.2H3O4P/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14;2*1-5(2,3)4/h4,6,8-11,18H,3,5,7,16H2,1-2H3;2*(H3,1,2,3,4)
InChIKeyGJOHLWZHWQUKAU-UHFFFAOYSA-N
Roles Classification
Biological Role:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
Application:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
ChEBI Ontology
Outgoing Relation(s)
Primaquine Phosphate (CHEBI:232993) has role antimalarial (CHEBI:38068)
Primaquine Phosphate (CHEBI:232993) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine;phosphoric acidSUBMITTER
MalquineSUBMITTER
NSC-149765ChEMBL
Primaquine bisphosphateSUBMITTER
Primaquini diphosphasChEMBL
WR 2975ChEMBL
Brand Name  Source
CamdenChEMBL
Registry NumbersSources
CAS:63-45-6SUBMITTER
Citations