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CHEBI:232545 - LCS3

Default Structure
ChEBI IDCHEBI:232545
ChEBI NameLCS3
Stars
DefinitionLCS3 is a reversible and uncompetitive glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) inhibitor (IC50=3.3 uM and 3.8 uM, respectively). LCS3 shows anti-tumor activity, and induces apoptosis. LCS3 can be used in lung adenocarcinoma (LUAD) research.
SubmitterBrianna Xu
DownloadsMolfile
FormulaC11H7ClN2O4
Net Charge0
Average Mass266.640
Monoisotopic Mass266.00943
SMILESO=[N+]([O-])c1ccc(/C(O)=N/c2ccc(Cl)cc2)o1
InChIInChI=1S/C11H7ClN2O4/c12-7-1-3-8(4-2-7)13-11(15)9-5-6-10(18-9)14(16)17/h1-6H,(H,13,15)
InChIKeyJDBZJNUHQINERI-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
LCS3 (CHEBI:232545) is a organic molecular entity (CHEBI:50860)
Synonyms  Source
N-(4-chlorophenyl)-5-nitro-2-furancarboxamideSUBMITTER
N-(4-chlorophenyl)-5-nitrofuran-2-carboxamideSUBMITTER
NSC761634SUBMITTER
Registry NumbersSources
CAS:109844-92-0SUBMITTER