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CHEBI:232058 - dCeMM4

ChEBI IDCHEBI:232058
ChEBI NamedCeMM4
Stars
DefinitionA furan that is substituted by {4-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}carbonyl and methyl groups at positions 2 and 5, respectively. It is a glue degrader that induces the ubiquitination and degradation of cyclin K by prompting an interaction between CDK12:cyclin K with a CRL4B ligase complex.
Last Modified7 October 2024
SubmitterBrianna Xu
DownloadsMolfile
FormulaC14H15N3O3S2
Net Charge0
Average Mass337.426
Monoisotopic Mass337.05548
SMILESCc1ccc(C(=O)N2CSCC2C(=O)Nc2ncc(C)s2)o1
InChIInChI=1S/C14H15N3O3S2/c1-8-3-4-11(20-8)13(19)17-7-21-6-10(17)12(18)16-14-15-5-9(2)22-14/h3-5,10H,6-7H2,1-2H3,(H,15,16,18)
InChIKeyBPWZJVKIVHVVHP-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
dCeMM4 (CHEBI:232058) is a 1,3-thiazoles (CHEBI:38418)
dCeMM4 (CHEBI:232058) is a furans (CHEBI:24129)
dCeMM4 (CHEBI:232058) is a secondary carboxamide (CHEBI:140325)
dCeMM4 (CHEBI:232058) is a tertiary carboxamide (CHEBI:140326)
dCeMM4 (CHEBI:232058) is a thiazolidines (CHEBI:35622)
IUPAC Name 
3-[(5-methylfuran-2-yl)carbonyl]-N-(5-methyl-1,3-thiazol-2-yl)-1,3-thiazolidine-4-carboxamide
Registry NumbersSources
CAS:1281683-44-0SUBMITTER
Citations