EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:231793 - ODN 2216

Default Structure
ChEBI IDCHEBI:231793
ChEBI NameODN 2216
Stars
DefinitionODN 2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. ODN 2216 induces high amounts of IFN-a and IFN-b. ODN2216 induces IFN-a by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). ODN 2216 stimulates IFN-y production in peripheral blood mononuclear cells (PBMC), which is indirect and mediated by IFN-a/b. ODN 2216 can activate NK cells and promote IFN-y production of TCR-triggered CD4+ T cells. (MedChemExpress)
Submitteramillett1
DownloadsMolfile
Formula
Net Charge0
Average Mass0.000
Monoisotopic Mass0.00000
ChEBI Ontology
Outgoing Relation(s)
ODN 2216 (CHEBI:231793) is a organic molecular entity (CHEBI:50860)
Synonym  Source
ODN2216SUBMITTER
Registry NumbersSources
CAS:332437-00-0SUBMITTER