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CHEBI:231703 - CHM-1

Default Structure
ChEBI IDCHEBI:231703
ChEBI NameCHM-1
Stars
DefinitionCHM-1, a microtubule-destabilizing agent, inhibits tubulin polymerization. CHM-1 is a potent and selective antimitotic antitumor activity against human hepatocellular carcinoma. CHM-1 induces growth inhibition and apoptosis via G2-M phase arrest in human hepatocellular carcinoma cells by activation of Cdc2 kinase activity. (MedChemExpress)
Submitteramillett1
DownloadsMolfile
FormulaC16H10FNO3
Net Charge0
Average Mass283.258
Monoisotopic Mass283.06447
SMILESO=c1cc(-c2ccccc2F)nc2cc3c(cc12)OCO3
InChIInChI=1S/C16H10FNO3/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12/h1-7H,8H2,(H,18,19)
InChIKeyZMYDAPJHGNEFGQ-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
CHM-1 (CHEBI:231703) is a organic molecular entity (CHEBI:50860)
Synonym  Source
6-(2-Fluorophenyl)[1,3]dioxolo[4,5-G]quinolin-8(5h)-OneSUBMITTER
Registry NumbersSources
CAS:154554-41-3SUBMITTER