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CHEBI:231676 - SF2523

ChEBI IDCHEBI:231676
ChEBI NameSF2523
Stars
DefinitionA member of the class of thienopyrans that is 7H-thieno[3,2-b]pyran-7-one substituted by 2,3-dihydro-1,4-benzodioxin-6-yl and morpholin-4-yl groups at positions 3 and 5, respectively. It is a dual inhibitor of PI3K and BRD4 that exhibits antineoplastic activity.
Last Modified9 August 2024
Submitteramillett1
DownloadsMolfile
FormulaC19H17NO5S
Net Charge0
Average Mass371.414
Monoisotopic Mass371.08274
SMILESO=c1cc(N2CCOCC2)oc2c(-c3ccc4c(c3)OCCO4)csc12
InChIInChI=1S/C19H17NO5S/c21-14-10-17(20-3-5-22-6-4-20)25-18-13(11-26-19(14)18)12-1-2-15-16(9-12)24-8-7-23-15/h1-2,9-11H,3-8H2
InChIKeyBYTKNUOMWLJVNQ-UHFFFAOYSA-N
Roles Classification
Biological Roles:
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor  An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
autophagy inducer  Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
bromodomain-containing protein 4 inhibitor  Any inhibitor of bromodomain-containing protein 4 (BRD4).
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
SF2523 (CHEBI:231676) has role anticoronaviral agent (CHEBI:149553)
SF2523 (CHEBI:231676) has role antineoplastic agent (CHEBI:35610)
SF2523 (CHEBI:231676) has role apoptosis inducer (CHEBI:68495)
SF2523 (CHEBI:231676) has role autophagy inducer (CHEBI:138880)
SF2523 (CHEBI:231676) has role bromodomain-containing protein 4 inhibitor (CHEBI:137114)
SF2523 (CHEBI:231676) has role EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor (CHEBI:50914)
SF2523 (CHEBI:231676) is a benzodioxine (CHEBI:64096)
SF2523 (CHEBI:231676) is a morpholines (CHEBI:38785)
SF2523 (CHEBI:231676) is a thienopyran (CHEBI:48910)
IUPAC Name 
3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one
Synonyms  Source
3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-morpholino-7H-thieno[3,2-b]pyran-7-oneSUBMITTER
3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(4-morpholinyl)-7H-thieno[3,2-b]pyran-7-oneChEBI
SF 2523ChEBI
SF-2523ChEBI
Manual XrefsDatabases
82VPDBeChem
Registry NumbersSources
CAS:1174428-47-7ChEBI
Citations