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CHEBI:231676 - SF2523

Default Structure
ChEBI IDCHEBI:231676
ChEBI NameSF2523
Stars
DefinitionA member of the class of thienopyrans that is 7H-thieno[3,2-b]pyran-7-one substituted by 2,3-dihydro-1,4-benzodioxin-6-yl and morpholin-4-yl groups at positions 3 and 5, respectively. It is a dual inhibitor of PI3K and BRD4 that exhibits antineoplastic activity.
Last Modified9 August 2024
Submitteramillett1
DownloadsMolfile
FormulaC19H17NO5S
Net Charge0
Average Mass371.414
Monoisotopic Mass371.08274
SMILESO=c1cc(N2CCOCC2)oc2c(-c3ccc4c(c3)OCCO4)csc12
InChIInChI=1S/C19H17NO5S/c21-14-10-17(20-3-5-22-6-4-20)25-18-13(11-26-19(14)18)12-1-2-15-16(9-12)24-8-7-23-15/h1-2,9-11H,3-8H2
InChIKeyBYTKNUOMWLJVNQ-UHFFFAOYSA-N
Roles Classification
Biological Roles:
bromodomain-containing protein 4 inhibitor  Any inhibitor of bromodomain-containing protein 4 (BRD4).
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
autophagy inducer  Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor  An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
SF2523 (CHEBI:231676) has role anticoronaviral agent (CHEBI:149553)
SF2523 (CHEBI:231676) has role antineoplastic agent (CHEBI:35610)
SF2523 (CHEBI:231676) has role apoptosis inducer (CHEBI:68495)
SF2523 (CHEBI:231676) has role autophagy inducer (CHEBI:138880)
SF2523 (CHEBI:231676) has role bromodomain-containing protein 4 inhibitor (CHEBI:137114)
SF2523 (CHEBI:231676) has role EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor (CHEBI:50914)
SF2523 (CHEBI:231676) is a benzodioxine (CHEBI:64096)
SF2523 (CHEBI:231676) is a morpholines (CHEBI:38785)
SF2523 (CHEBI:231676) is a thienopyran (CHEBI:48910)
IUPAC Name 
3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one
Synonyms  Source
3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(4-morpholinyl)-7H-thieno[3,2-b]pyran-7-oneChEBI
3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-morpholino-7H-thieno[3,2-b]pyran-7-oneSUBMITTER
SF 2523ChEBI
SF-2523ChEBI
Manual XrefsDatabases
82VPDBeChem
Registry NumbersSources
CAS:1174428-47-7ChEBI
Citations