EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
We are looking for a new Chemistry curator to join the ChEBI team. Find out more about it here.
CHEBI:231614 - Nivolumab
| ChEBI ID | CHEBI:231614 |
| ChEBI Name | Nivolumab |
| Stars | |
| Definition | Nivolumab is a human monoclonal antibody for Programmed Death Receptor-1 (PD-1). It is a targeted immunotherapy treatment against metastatic cancer. |
| Submitter | amillett1 |
| Roles Classification |
|---|
| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Nivolumab (CHEBI:231614) has role anti-HBV agent (CHEBI:64951) |
| Nivolumab (CHEBI:231614) has role anti-HIV agent (CHEBI:64946) |
| Nivolumab (CHEBI:231614) has role antineoplastic agent (CHEBI:35610) |
| Nivolumab (CHEBI:231614) has role antiviral agent (CHEBI:22587) |
| Nivolumab (CHEBI:231614) has role cardiovascular drug (CHEBI:35554) |
| Nivolumab (CHEBI:231614) is a organic molecular entity (CHEBI:50860) |
| Synonyms | Source |
|---|---|
| Anti-PD-1 human monoclonal antibody MDX-1106 | SUBMITTER |
| BMS-936558 | ChEMBL |
| BMS-986298 | ChEMBL |
| MDX-1106 | ChEMBL |
| MDX1106 | ChEMBL |
| Nivolumab | ChEMBL |
| Brand Names | Source |
|---|---|
| Nivolumab bms | ChEMBL |
| Nivolumab component of bms-986213 | ChEMBL |
| Nivolumab component of opdualag | ChEMBL |
| Opdivo | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| CAS:946414-94-4 | SUBMITTER |