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CHEBI:231355 - tasquinimod

Default Structure
ChEBI IDCHEBI:231355
ChEBI Nametasquinimod
Stars
DefinitionTasquinimod is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.
Submitterdelphine
DownloadsMolfile
FormulaC20H17F3N2O4
Net Charge0
Average Mass406.360
Monoisotopic Mass406.11404
SMILESCOc1cccc2c1c(O)c(C(=O)N(C)c1ccc(C(F)(F)F)cc1)c(=O)n2C
InChIInChI=1S/C20H17F3N2O4/c1-24(12-9-7-11(8-10-12)20(21,22)23)18(27)16-17(26)15-13(25(2)19(16)28)5-4-6-14(15)29-3/h4-10,26H,1-3H3
InChIKeyONDYALNGTUAJDX-UHFFFAOYSA-N
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
tasquinimod (CHEBI:231355) has role antineoplastic agent (CHEBI:35610)
tasquinimod (CHEBI:231355) is a organic molecular entity (CHEBI:50860)
INN  Source
tasquinimodWHO MedNet
Synonym  Source
ABR-215050SUBMITTER
Registry NumbersSources
CAS:254964-60-8SUBMITTER
Citations