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CHEBI:230497 - PLX5622

Default Structure
ChEBI IDCHEBI:230497
ChEBI NamePLX5622
Stars
DefinitionPLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor. PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. PLX5622 is mostly used in the way of feed free diet.
Submitterdelphine
DownloadsMolfile
FormulaC21H19F2N5O
Net Charge0
Average Mass395.413
Monoisotopic Mass395.15577
SMILESCOc1ncc(F)cc1CNc1ccc(Cc2cnc3ncc(C)cc23)c(F)n1
InChIInChI=1S/C21H19F2N5O/c1-12-5-17-14(9-26-20(17)25-8-12)6-13-3-4-18(28-19(13)23)24-10-15-7-16(22)11-27-21(15)29-2/h3-5,7-9,11H,6,10H2,1-2H3,(H,24,28)(H,25,26)
InChIKeyNSMOZFXKTHCPTQ-UHFFFAOYSA-N
ChEBI Ontology
Outgoing Relation(s)
PLX5622 (CHEBI:230497) is a organic molecular entity (CHEBI:50860)
Registry NumbersSources
CAS:1303420-67-8SUBMITTER