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CHEBI:230494 - GSK547

Default Structure
ChEBI IDCHEBI:230494
ChEBI NameGSK547
Stars
DefinitionGSK547 (GSK'547) is a highly selective and potent inhibitor of receptor-interacting serine/threonine protein kinase 1 (RIPK1), inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.
Submitterdelphine
DownloadsMolfile
FormulaC20H18F2N6O
Net Charge0
Average Mass396.401
Monoisotopic Mass396.15102
SMILESN#Cc1cc(N2CCC(C(=O)N3N=CC[C@H]3c3cc(F)cc(F)c3)CC2)ncn1
InChIInChI=1S/C20H18F2N6O/c21-15-7-14(8-16(22)9-15)18-1-4-26-28(18)20(29)13-2-5-27(6-3-13)19-10-17(11-23)24-12-25-19/h4,7-10,12-13,18H,1-3,5-6H2/t18-/m0/s1
InChIKeySJVGFKBLUYAEOK-SFHVURJKSA-N
ChEBI Ontology
Outgoing Relation(s)
GSK547 (CHEBI:230494) is a organic molecular entity (CHEBI:50860)
Synonym  Source
GSK'547SUBMITTER
Registry NumbersSources
CAS:2226735-55-1SUBMITTER